NLR/LMR/PLR与胃癌患者预后的相关研究
Correlation between NLR/LMR/PLR and Prognosis of Patients with Gastric Cancer
DOI: 10.12677/ACM.2022.125614, PDF,  被引量   
作者: 胡希阳, 徐新倩:青海大学,青海 西宁;骆玉霜:青海大学附属医院,青海 西宁
关键词: 炎性生物标记物胃癌预后相关性Biomarkers of Inflammation Gastric Cancer Prognosis Correlation
摘要: 胃恶性肿瘤是消化系统常见的恶性肿瘤之一,我国大部分胃癌患者在初诊时就已经处于晚期阶段,临床和病理分期系统一直是预测肿瘤患者治疗疗效及预后的主要参考依据,这些系统是基于肿瘤的影像学或活检及其免疫组化。但是,外周血中的生物标志物标本易于获取,检测方法简单可靠易行,其在肿瘤诊断、治疗及预后评估等方面的作用受到广泛关注。目前,已有证据表明,炎症生物标记物与肿瘤微环境密切相关。因此,NLR、LMR、PLR对胃癌患者的预后有一定的预测价值,是肿瘤患者预后的潜在指标。
Abstract: Gastric cancer is a common malignant tumor of the digestive system. Most gastric cancer patients in China are already in the advanced stage when they are first diagnosed. The clinical and pathological staging system has always been the main reference for predicting the therapeutic efficacy and prognosis of cancer patients, and these systems are based on tumor imaging or biopsy and im-munohistochemistry. However, the biomarker samples of peripheral blood are easy to obtain and the detection method is simple, and its role in tumor diagnosis, treatment and prognosis evaluation has been widely concerned. At present, there is evidence that inflammatory biomarkers are closely related to the tumor microenvironment. Therefore, NLR, LMR and PLR have certain predictive value for the prognosis of gastric cancer patients, and are potential prognostic indicators of cancer pa-tients.
文章引用:胡希阳, 骆玉霜, 徐新倩. NLR/LMR/PLR与胃癌患者预后的相关研究[J]. 临床医学进展, 2022, 12(5): 4240-4245. https://doi.org/10.12677/ACM.2022.125614

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