西宁地区OSAHS患者相关危险因素及治疗进展
OSAHS Related Risk Factors and Treatment Progress in Xining Area
摘要: 阻塞性睡眠呼吸暂停低通气综合征是一种常见的慢性呼吸障碍性疾病，与年龄、吸烟、肥胖、高血压等多种因素相关。随着疾病的进展，易诱发一系列心血管风险和内分泌代谢紊乱，严重威胁人们身心健康。从诊疗及评估预后的角度看，阻塞性睡眠呼吸暂停被认为是一种需要精准医学治疗的疾病。CPAP是目前最常见的一种治疗方案，受到人们广泛关注。由于其依从性限制，需要临床医生根据患者疾病严重程度制定个体化方案。
Abstract: Obstructive sleep apnea hypopneasyndrome (OSAHS) is a common chronic respiratory disorder as-sociated with age, smoking, obesity, hypertension and other factors. With the development of the disease, it is easy to induce a series of cardiovascular risks and endocrine and metabolic disorders, seriously threatening people’s physical and mental health. From the perspective of diagnosis, treatment and prognosis, obstructive sleep apnea is considered as a disease requiring precision medicine treatment. CPAP is one of the most common treatment options and has attracted wide-spread attention. Due to compliance limitations, clinicians are required to tailor individual proto-cols to the severity of the patient’s disease.
文章引用：张聪慧, 冯恩志. 西宁地区OSAHS患者相关危险因素及治疗进展[J]. 临床医学进展, 2022, 12(5): 4331-4336. https://doi.org/10.12677/ACM.2022.125627

参考文献

[1] Chang, H.P., Chen, Y.F. and Du, J.K. (2020) Obstructive Sleep Apnea Treatment in Adults. The Kaohsiung Journal of Medical Sciences, 36, 7-12. [Google Scholar] [CrossRef] [PubMed]
[2] Berry, R.B., Budhiraja, R., Gottlieb, D.J., Gozal, D., Iber, C., Kapur, V.K., et al. (2012) Rules for Scoring Respiratory Events in Sleep: Update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events: Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. Journal of Clinical Sleep Medicine, 8, 597-619. [Google Scholar] [CrossRef] [PubMed]
[3] Poka-Mayap, V., Balkissou Adamou, D., Massongo, M., Voufouo Sonwa, S., Alime, J., Moutlen, B.P.M., et al. (2020) Obstructive Sleep Apnea and Hypopnea Syndrome in Patients Admitted in a Tertiary Hospital in Cameroon: Prevalence and Associated Factors. PLoS ONE, 15, e0227778. [Google Scholar] [CrossRef] [PubMed]
[4] Senaratna, C.V., Perret, J.L., Lodge, C.J., Lowe, A.J., Camp-bell, B.E., Matheson, M.C., et al. (2017) Prevalence of Obstructive Sleep Apnea in the General Population: A Systematic Review. Sleep Medicine Reviews, 34, 70-81. [Google Scholar] [CrossRef] [PubMed]
[5] 邓永君, 鲁建光, 胡欣, 陈伟刚. 阻塞性睡眠呼吸暂停低通气综合征患者血清代谢指标分析及其临床意义[J]. 临床耳鼻咽喉头颈外科杂志, 2014, 28(12): 848-851.
[6] 刘玉霜, 高巍. 导致阻塞性睡眠呼吸暂停低通气综合征发生的相关影响因素分析[J]. 当代医药论丛, 2021, 19(8): 28-29.
[7] 王洪洪, 李进让, 赵鹏举, 陈曦, 马宁, 章榕. 成年阻塞性睡眠呼吸暂停低通气综合征患者体重指数与颈围的性别差异分析[J]. 临床误诊误治, 2016, 29(4): 94-96.
[8] 孙如坤, 刘岩, 潘春香, 胡祥坤, 王艳杰. 不同年龄阻塞性睡眠呼吸暂停低通气综合征患者多导睡眠监测结果分析[J]. 临床医学工程, 2021, 28(10): 1441-1442.
[9] 李金宝, 柴多. 高海拔地区阻塞性睡眠呼吸暂停低通气综合征患者肺功能检测分析[J]. 高原医学杂志, 2016, 26(2): 26-28.
[10] 张润, 王茂筠, 王怡唯, 胡碧, 雷飞, 梁宗安. 肥胖程度及睡眠体位对阻塞性睡眠呼吸暂停低通气综合征患者的影响研究[J]. 中国全科医学, 2017, 20(11): 1294-1299.
[11] Mortimore, I.L., Marshall, I., Wraith, P.K., Sellar, R.J. and Dougla, N.J. (1998) Neck and Total Body Fat Deposition in Nonobese and Obese Patients with Sleep Apnea Compared with That in Control Subjects. American Journal of Respiratory and Critical Care Medicine, 157, 280-283. [Google Scholar] [CrossRef] [PubMed]
[12] Balachandran, J.S., Masa, J.F. and Mokhlesi, B. (2014) Obesity Hypoventilation Syndrome: Epidemiology and Diagnosis. Sleep Medicine Clinics, 9, 341-347. [Google Scholar] [CrossRef] [PubMed]
[13] Forcelini, C.M., Buligon, C.M., Costa, G.J.K., Petter, G.D.C., Scapin, H.P., Augustin, I.A., Dal-Piva, L.D.M., et al. (2019) Age-Dependent Influence of Gender on Symptoms of Obstructive Sleep Apnea in Adults. Sleep Science, 12, 132-137. [Google Scholar] [CrossRef] [PubMed]
[14] Benjafield, A.V., Ayas, N.T., Eastwood, P.R., Heinzer, R., Ip, M.S.M., Morrell, M.J., Nunez, C.M., Patel, S.R., Penzel, T., Pépin, J.L., Peppard, P.E., Sinha, S., Tufik, S., Valentine, K. and Malhotra, A. (2019) Estimation of the Global Prevalence and Burden of Obstructive Sleep Apnoea: A Litera-ture-Based Analysis. The Lancet Respiratory Medicine, 7, 687-698. [Google Scholar] [CrossRef] 
[15] 王春艳, 韩芳, 何权瀛, 李静, 韩旭, 贾非. 阻塞性睡眠呼吸暂停低通气综合征白天高碳酸血症相关因素的研究[J]. 贵州医药, 2007, 31(4): 306-309.
[16] 魏月. 肥胖OSAHS患者睡眠期经皮CO2分压监测的研究[D]: [硕士学位论文]. 上海: 上海交通大学, 2014.
[17] 刘栖如. OSAHS患者病情程度影响因素分析[J]. 中国医学前沿杂志(电子版), 2017, 9(10): 209-212.
[18] Kaw, R., Her-nandez, A.V., Walker, E., Aboussouan, L. and Mokhlesi, B. (2009) Determinants of Hypercapnia in Obese Patients with Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis of Cohort Studies. Chest, 136, 787-796. [Google Scholar] [CrossRef] [PubMed]
[19] Charčiūnaitė, K., Gauronskaitė, R., Šlekytė, G., Danila, E. and Zablockis, R. (2021) Evaluation of Obstructive Sleep Apnea Phenotypes Treatment Effectiveness. Medicina, 57, Article No. 335. [Google Scholar] [CrossRef] [PubMed]
[20] Younes, M., Ostrowski, M., Thompson, W., Leslie, C. and Shewchuk, W. (2001) Chemical Control Stability in Patients with Obstructive Sleep Apnea. American Journal of Respiratory and Critical Care Medicine, 163, 1181-1190. [Google Scholar] [CrossRef] [PubMed]
[21] Nishida, K., Lanspa, M.J., Cloward, T.V., Weaver, L.K., Brown, S.M., Bell, J.E., et al. (2015) Effects of Positive Airway Pressure on Patients with Obstructive Sleep Apnea during Acute Ascent to Altitude. Annals of the American Thoracic Society, 12, 1072-1078. [Google Scholar] [CrossRef] 
[22] 刘洪千. 青海地区阻塞性睡眠呼吸暂停低通气综合征与外周气道阻力的相关性分析[D]: [硕士学位论文]. 青海: 青海大学, 2020.
[23] 何忠明, 郭红, 吕云辉, 李剑平, 蒋雪龙. 不同海拔地区OSAHS患者呼吸紊乱情况初步探讨[J]. 国际呼吸杂志, 2017, 37(20): 1521-1525.
[24] 赵振, 张莉媛, 多杰. 不同海拔藏族OSAHS患者血清IL-18、MMP-9及TIMP-1的表达及意义[J]. 临床肺科杂志, 2018, 23(3): 462-466.
[25] Laratta, C.R., Ayas, N.T., Povitz, M. and Pendharkar, S.R. (2017) Diagnosis and Treat-ment of Obstructive Sleep Apnea in Adults. Canadian Medical Association Journal, 189, E1481-E1488. [Google Scholar] [CrossRef] [PubMed]
[26] 非接触式睡眠呼吸监测仪可用于OSA患者的筛查和诊断[J]. 中华医学信息导报, 2021, 36(21): 8. [Google Scholar] [CrossRef] 
[27] Mazzotti, D.R., Lim, D.C., Sutherland, K., Bitten-court, L., Mindel, J.W., Magalang, U., et al. (2018) Opportunities for Utilizing Polysomnography Signals to Characterize Obstructive Sleep Apnea Subtypes and Severity. Physiological Measurement, 39, 09TR01. [Google Scholar] [CrossRef] [PubMed]
[28] 杨生岳, 冯恩志, 张瑛, 姚顺清, 陈宗茹. CPAP对高原地区OSAHS患者氧化应激的干预作用[J]. 临床肺科杂志, 2013, 18(11): 1958-1960.
[29] Pack, A.I. (2016) Application of Personalized, Predictive, Preventative, and Participatory (P4) Medicine to Obstructive Sleep Apnea. A Roadmap for Improving Care? Annals of the American Thoracic Society, 13, 1456-1467. [Google Scholar] [CrossRef] 

为你推荐