胶原蛋白相关材料对烧伤创面的影响研究进展

Research Progress on the Effect of Collagen-Related Materials on Burn Wound

摘要: 烧伤是最严重的危重疾病之一，与广泛和长期的身体代谢和精神障碍有关。烧伤后，皮肤会失去其保护功能，使身体容易出现许多并发症。烧伤伤口的金标准治疗方法是自体皮肤移植；然而，由于供体皮肤的量不足，可能并不总是这一种选择。伤口敷料可用作非皮肤移植的患者的主要治疗方法。许多不同的材料用于制作敷料；目前的材料包括胶原蛋白、水胶体、海藻酸盐、水凝胶和透明质酸等。目前还没有被业界所普遍接受的烧伤敷料黄金标准。理想的伤口敷料应具备诸如基本特性，如生物相容性、保湿性、透气性等基本特殊，以便于最佳性能。并且，胶原蛋白已被证明具有很多的有益特性，并且有利于烧伤患者使用。笔者收集了胶原蛋白敷料应用于烧伤创面的相关文献，包括其临床应用和进展。相关研究结果表明，胶原蛋白相关材料对烧伤创面有积极的影响。

Abstract: Burns is one of the most serious and critical diseases associated with widespread and long-term physical, metabolic, and mental disorders. After Burns, the skin loses its protective properties, making the body susceptible to many complications. The gold standard of treatment for burn wounds is autologous skin grafting; however, this may not always be an option due to insufficient donor skin. Wound dressings may be used as the primary treatment for patients who are not suita-ble for skin grafts. Many different materials are used to make dressings; current materials include hydrocolloids, alginate, hydrogels, Collagen, and hyaluronic acid. There is no universally accepted gold standard for burn dressings. Ideal wound dressings should have other basic properties, such as Biocompatibility, moisture retention, breathability, etc., for optimum performance. However, Colla-gen has been shown to have a number of beneficial properties and is beneficial for use in burn pa-tients. We collected the literature on the application of Collagen dressings to burn wounds, includ-ing their clinical application and progress. The results show that Collagen material has a positive effect on burn wounds.