胃癌组织中HER2、CD10的表达及与HP感染的关系
Relationship between Human Epidermal Growth Factor Receptor 2 and CD10 Expression and Hp Infection of Gastric Carcinoma Histology
DOI: 10.12677/ACM.2022.125678, PDF,    科研立项经费支持
作者: 武先蓉, 高建丽, 曾 宁：青海大学研究生院，青海 西宁；马臻棋*, 王学红：青海大学附属医院消化内科，青海 西宁
关键词: 胃癌；表皮生长因子受体2；CD10；幽门螺杆菌感染；肠上皮化生；Gastric Cancer； Human Epidermal Growth Factor Receptor 2； CD10； Helicobacter pylori； Intestinal Metaplasia
摘要: 我国胃癌的发病率逐年升高，但目前对于胃癌的早期发现仍缺乏有效的手段。近年来有研究发现HER2及CD10的异常表达与胃癌的发生有相关性且与Hp感染关系密切。本文就HER2及CD10在胃癌发病机制中的作用及与HP感染的相关性进行综述，为发现治疗胃癌的潜在靶点提供参考依据。
Abstract: The incidence of gastric cancer in my country is increasing year by year. However, there is still a lack of effective methods for early detection of gastric cancer. In recent years, related studies have found that the abnormal expression of HER2 and CD10 is related to occurrence of gastric cancer and is closely related to HP infection. This article reviews the roles of HER2 and CD10 in the pathogene-sis of gastric cancer and their correlation with Hp infection, in order to provide theoretical basis for early detection of gastric cancer patients.
文章引用：武先蓉, 马臻棋, 王学红, 高建丽, 曾宁. 胃癌组织中HER2、CD10的表达及与HP感染的关系[J]. 临床医学进展, 2022, 12(5): 4686-4691. https://doi.org/10.12677/ACM.2022.125678

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