急性一氧化碳中毒患者动脉血乳酸水平对心肌损伤的预测价值

The Predictive Value of Arterial Blood Lactate Level on Myocardial Injury in Patients with Acute Carbon Monoxide Poisoning

摘要: 目的：探讨急性一氧化碳中毒患者动脉血乳酸水平对心肌损伤的预判价值。方法：分析136例急性一氧化碳中毒患者动脉血乳酸水平同心肌酶之间的关系；根据乳酸水平 < 2 mmol/L、2~4 mmol/L及 > 4 mmol/L进行病例分组，这三组患者病例数分别为57例，42例，37例；进行各组患者心肌酶水平的比较。结果：随着血乳酸水平的升高，肌酸激酶、肌酸激酶同工酶、乳酸脱氢酶、羟丁酸脱氢酶指标均呈上升趋势，且与血乳酸水平呈正相关。结论：急性一氧化碳中毒患者动脉血乳酸与心肌酶各指标呈正相关，血乳酸水平越高，心肌损伤越重；动脉血乳酸水平对心肌损伤有预判价值。

Abstract: Objective: To explore the predictive value of arterial blood lactate level on myocardial injury in pa-tients with acute carbon monoxide poisoning. Methods: To analyze the relationship between arteri-al blood lactate levels and myocardial enzymes in 136 patients with acute carbon monoxide poi-soning; According to lactate level <2 mmol/L, 2~4 mmol/L and >4 mmol/L case grouping, the numbers of patients in these three groups were 57, 42, and 37, respectively; The myocardial en-zyme levels of patients in each group were compared. Results: With the increase of blood lactate level, the indexes of creatine kinase, creatine kinase isoenzyme, lactate dehydrogenase and hy-droxybutyrate dehydrogenase all showed an upward trend, and were positively correlated with blood lactate level. Conclusion: In patients with acute carbon monoxide poisoning, arterial blood lactate was positively correlated with various indexes of myocardial enzymes. The higher the blood lactate level, the more severe the myocardial injury. The arterial blood lactate level has predictive value for myocardial injury.