MHR与慢性阻塞性肺疾病合并动脉粥样硬化的研究进展
Research Progress of MHR and Atherosclerosis in Chronic Obstructive Pulmonary Disease
DOI: 10.12677/ACM.2022.125691, PDF,   
作者: 王茵茵：青海大学，青海 西宁；左小芹：青海大学附属医院，青海 西宁
关键词: MHR；氧化应激；慢性阻塞性肺疾病；动脉粥样硬化；MHR； Oxidative Stress； Chronic Obstructive Pulmonary Disease； Atherosclerosis
摘要: 炎性反应、氧化应激、血管内皮细胞功能损伤、缺氧及遗传等是慢性阻塞性肺疾病(chronic ob-structive pulmonary disease, COPD)及其并发症的重要病理生理基础，目前尚缺乏能综合反映上述机制且廉价、易获得的标记物来评估COPD及其并发症。单核细胞与高密度脂蛋白胆固醇比值(ratio of monocytes to high-density lipoprotein cholesterol, MHR)被认为是一种能反映炎症、氧化应激及心血管疾病预后的重要标志物，而COPD本病或其并发症也与心血管不良事件密切相关。
Abstract: Inflammatory response, oxidative stress, vascular endothelial cell dysfunction, hypoxia and heredi-ty are important pathophysiological bases of chronic obstructive pulmonary disease (COPD) and its complications. At present, there is a lack of inexpensive and readily available markers that reflect these mechanisms to evaluate COPD and its complications. The ratio of monocytes to high-density lipoprotein cholesterol (MHR) is considered to be an important marker of inflammation, oxidative stress and prognosis of cardiovascular diseases. COPD or its complications are also closely associat-ed with cardiovascular adverse events.
文章引用：王茵茵, 左小芹. MHR与慢性阻塞性肺疾病合并动脉粥样硬化的研究进展[J]. 临床医学进展, 2022, 12(5): 4765-4769. https://doi.org/10.12677/ACM.2022.125691

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