细胞外基质在结直肠癌中的研究进展
Advances in the Study of Extracellular Matrix in Colorectal Cancer
DOI: 10.12677/MD.2022.122016, PDF,    科研立项经费支持
作者: 齐晓鹏, 许正杰:大理大学临床医学院,云南 大理;谭云波, 舒武英*:大理大学第一附属医院,云南 大理
关键词: 细胞外基质结直肠恶性肿瘤恶性肿瘤细胞凋亡Extracellular Matrix Colorectal Malignancy Malignancy Apoptosis
摘要: 细胞外基质作为细胞直接的生存环境,与结直肠癌恶性肿瘤的发生发展密切相关。由于细胞外基质是有多种蛋白及多糖分子构成,因此,细胞外基质与结直肠癌的发生发展有着密切关系,并且在结直肠癌的转移、侵袭、凋亡、耐药和发病相关的信号通路中都扮演着很重要的角色。
Abstract: Extracellular matrix, as the direct living environment of cells, is closely related to the development of colorectal cancer malignancies. Since the extracellular matrix is composed of various protein and polysaccharide molecules, it is closely related to the development of colorectal cancer and plays a very important role in the metastasis, invasion, apoptosis, drug resistance and pathogenesis-related signaling pathways of colorectal cancer.
文章引用:齐晓鹏, 谭云波, 舒武英, 许正杰. 细胞外基质在结直肠癌中的研究进展[J]. 医学诊断, 2022, 12(2): 101-106. https://doi.org/10.12677/MD.2022.122016

参考文献

[1] 刘宗超, 李哲轩, 张阳, 周彤, 张婧莹, 游伟程, 等. 2020全球癌症统计报告解读[J]. 肿瘤综合治疗电子杂志, 2021, 7(2): 1-13.
[2] Jiang, Y., Yuan, H., Li, Z., et al. (2021) Global Pattern and Trends of Colorectal Cancer Survival: A Systematic Review of Population-Based Registration Data. Cancer Biology & Medicine, 19, 175-186. [Google Scholar] [CrossRef] [PubMed]
[3] Song, M., Chan, A.T. and Sun, J. (2020) Influence of the Gut Microbiome, Diet, and Environment on Risk of Colorectal Cancer. Gastroenterology, 158, 322-340. [Google Scholar] [CrossRef] [PubMed]
[4] Biteau, B., Hochmuth, C.E. and Jasper, H. (2011) Maintaining Tissue Homeostasis: Dynamic Control of Somatic Stem Cell Activity. Cell Stem Cell, 9, 402-411. [Google Scholar] [CrossRef] [PubMed]
[5] Mohan, V., Das, A. and Sagi, I. (2020) Emerging Roles of ECM Remodeling Processes in Cancer. Seminars in Cancer Biology, 62, 192-200. [Google Scholar] [CrossRef] [PubMed]
[6] Lamandé, S.R. and Bateman, J.F. (2020) Genetic Disorders of the Extracellular Matrix. The Anatomical Record, 303, 1527-1542. [Google Scholar] [CrossRef] [PubMed]
[7] Lochter, A. and Bissell, M.J. (1995) Involvement of Extracellular Matrix Constituents in Breast Cancer. Seminars in Cancer Biology, 6, 165-173. [Google Scholar] [CrossRef] [PubMed]
[8] Canty, E.G. and Kadler, K.E. (2005) Procollagen Trafficking, Processing and Fibrillogenesis. Journal of Cell Science, 118, 1341-1353. [Google Scholar] [CrossRef] [PubMed]
[9] Bonnans, C., Chou, J. and Werb, Z. (2014) Remodelling the Extracellular Matrix in Development and Disease. Nature Reviews Molecular Cell Biology, 15, 786-801. [Google Scholar] [CrossRef] [PubMed]
[10] Ingber, D.E., Dike L, Hansen L, et al. (1994) Cellular Tensegrity: Exploring How Mechanical Changes in the Cytoskeleton Regulate Cell Growth, Migration, and Tissue Pattern during Morphogenesis. International Review of Cytology, 150, 173-224. [Google Scholar] [CrossRef
[11] Roskelley, C.D., Desprez, P.Y. and Bissell, M.J. (1994) Extracellular Matrix-Dependent Tissue-Specific Gene Expression in Mammary Epithelial Cells Requires Both Physical and Biochemical Signal Transduction. Proceedings of the National Academy of Sciences of the United States of America, 91, 12378-12382. [Google Scholar] [CrossRef] [PubMed]
[12] Conklin, M.W., Eickhoff, J.C., Riching, K.M., et al. (2011) Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma. The American Journal of Pathology, 178, 1221-1232. [Google Scholar] [CrossRef] [PubMed]
[13] Naba, A., Clauser, K.R., Lamar, J.M., et al. (2014) Extracellular Matrix Signatures of Human Mammary Carcinoma Identify Novel Metastasis Promoters. eLife, 3, Article ID: e01308. [Google Scholar] [CrossRef
[14] Wang, J., Deng, L., Huang, J., et al. (2017) High Expression of Fibronectin 1 Suppresses Apoptosis through the NF-κB Pathway and Is Associated with Migration in Nasopharyngeal Carcinoma. American Journal of Translational Research, 9, 4502-4511.
[15] Sun, Y., Zhao, C., Ye, Y., et al. (2020) High Expression of Fibronectin 1 Indicates Poor Prognosis in Gastric Cancer. Oncology Letters, 19, 93-102. [Google Scholar] [CrossRef] [PubMed]
[16] Wan, M.L., Wang, Y., Zeng, Z., et al. (2020) Colorectal Cancer (CRC) as a Multifactorial Disease and Its Causal Correlations with Multiple Signaling Pathways. Bioscience Reports, 40, BSR20200265. [Google Scholar] [CrossRef
[17] Qin, Y., Shembrey, C., Smith, J., et al. (2020) Laminin 521 Enhances Self-Renewal via STAT3 Activation and Promotes Tumor Progression in Colorectal Cancer. Cancer Letters, 476, 161-169. [Google Scholar] [CrossRef] [PubMed]
[18] Wang, Y., Xu, X., Marshall, J.E., et al. (2021) Loss of Hyaluronan and Proteoglycan Link Protein-1 Induces Tumorigenesis in Colorectal Cancer. Frontiers in Oncology, 11, Article ID: 754240. [Google Scholar] [CrossRef] [PubMed]
[19] Li, J., Xu, X., Jiang, Y., et al. (2020) Elastin Is a Key Factor of Tumor Development in Colorectal Cancer. BMC Cancer, 20, Article No. 217. [Google Scholar] [CrossRef] [PubMed]
[20] Wang, L.F., Liu, Y.S., Yang, B., et al. (2018) The Extracellular Matrix Protein Mindin Attenuates Colon Cancer Progression by Blocking Angiogenesis via Egr-1-Mediated Regulation. Oncogene, 37, 601-615. [Google Scholar] [CrossRef] [PubMed]
[21] Heo, J.H., Song, J.Y., Jeong, J.Y., et al. (2016) Fibulin-5 Is a Tumour Suppressor Inhibiting Cell Migration and Invasion in Ovarian Cancer. Journal of Clinical Pathology, 69, 109-116. [Google Scholar] [CrossRef] [PubMed]
[22] Hu, Z., Ai, Q., Xu, H., et al. (2011) Fibulin-5 Is Down-Regulated in Urothelial Carcinoma of Bladder and Inhibits Growth and Invasion of Human Bladder Cancer Cell Line 5637. Urologic Oncology, 29, 430-435. [Google Scholar] [CrossRef] [PubMed]
[23] Chen, X., Song, X., Yue, W., et al. (2015) Fibulin-5 Inhibits Wnt/β-Catenin Signaling in Lung Cancer. Oncotarget, 6, 15022-15034. [Google Scholar] [CrossRef] [PubMed]
[24] Tang, J.C., Liu, J.H., Liu, X.L., et al. (2015) Effect of Fibulin-5 on Adhesion, Migration and Invasion of Hepatocellular Carcinoma Cells via an Integrin-Dependent Mechanism. World Journal of Gastroenterology, 21, 11127-11140. [Google Scholar] [CrossRef] [PubMed]
[25] Mohamedi, Y., Fontanil, T., Solares, L., et al. (2016) Fibulin-5 Downregulates Ki-67 and Inhibits Proliferation and Invasion of Breast Cancer Cells. International Journal of Oncology, 48, 1447-1456. [Google Scholar] [CrossRef] [PubMed]
[26] Shi, X.Y., Wang, L., Cao, C.H., et al. (2014) Effect of Fibulin-5 on Cell Proliferation and Invasion in Human Gastric Cancer Patients. Asian Pacific Journal of Tropical Medicine, 7, 787-791. [Google Scholar] [CrossRef
[27] Chen, Y., Li, J., Jin, L., et al. (2019) Fibulin-5 Contributes to Colorectal Cancer Cell Apoptosis via the ROS/MAPK and Akt Signal Pathways by Downregulating Transient Receptor Potential Cation Channel Subfamily V Member 1. Journal of Cellular Biochemistry, 120, 17838-17846. [Google Scholar] [CrossRef] [PubMed]
[28] Hoshiba, T. and Tanaka, M. (2016) Decellularized Matrices as in Vitro Models of Extracellular Matrix in Tumor Tissues at Different Malignant Levels: Mechanism of 5-Fluorouracil Resistance in Colorectal Tumor Cells. Biochimica et Biophysica Acta, 1863, 2749-2757. [Google Scholar] [CrossRef] [PubMed]
[29] Maltseva, D., Raygorodskaya, M., Knyazev, E., et al. (2020) Knockdown of the α5 Laminin Chain Affects Differentiation of Colorectal Cancer Cells and Their Sensitivity to Chemotherapy. Biochimie, 174, 107-116. [Google Scholar] [CrossRef] [PubMed]
[30] Pankov, R. and Yamada, K.M. (2002) Fibronectin at a Glance. Journal of Cell Science, 115, 3861-3863. [Google Scholar] [CrossRef] [PubMed]
[31] Nuzzo, P.V., Buzzatti, G., Ricci, F., et al. (2014) Periostin: A Novel Prognostic and Therapeutic Target for Genitourinary Cancer? Clinical Genitourinary Cancer, 12, 301-311. [Google Scholar] [CrossRef] [PubMed]
[32] Kujawa, K.A., Zembala-Nożyńska, E., Cortez, A.J., et al. (2020) Fibronectin and Periostin as Prognostic Markers in Ovarian Cancer. Cells, 9, 149. [Google Scholar] [CrossRef] [PubMed]
[33] Yang, C., Cao, F., Huang, S., et al. (2021) Follistatin-Like 3 Correlates With Lymph Node Metastasis and Serves as a Biomarker of Extracellular Matrix Remodeling in Colorectal Cancer. Frontiers in Immunology, 12, Article ID: 717505. [Google Scholar] [CrossRef] [PubMed]
[34] Wu, X., Cai, J., Zuo, Z., et al. (2019) Collagen Facilitates the Colorectal Cancer Stemness and Metastasis through an Integrin/PI3K/AKT/Snail Signaling Pathway. Biomedicine & Pharmacotherapy, 114, Article ID: 108708. [Google Scholar] [CrossRef] [PubMed]
[35] Gordon-Weeks, A., Lim, S.Y., Yuzhalin, A., et al. (2019) Tumour-Derived Laminin α5 (LAMA5) Promotes Colorectal Liver Metastasis Growth, Branching Angiogenesis and Notch Pathway Inhibition. Cancers, 11, 630. [Google Scholar] [CrossRef] [PubMed]
[36] Reszegi, A., Horváth, Z., Karászi, K., et al. (2020) The Protective Role of Decorin in Hepatic Metastasis of Colorectal Carcinoma. Biomolecules, 10, 1199. [Google Scholar] [CrossRef] [PubMed]