进展期结直肠腺瘤化学预防的研究现状
Research Status of Chemoprevention in Advanced Colorectal Adenoma
DOI: 10.12677/ACM.2022.126745, PDF,    科研立项经费支持
作者: 高建丽, 武先蓉, 曾 宁:青海大学研究生院,青海 西宁;马臻棋*, 王学红:青海大学附属医院消化内科,青海 西宁
关键词: 进展期结直肠腺瘤晚期腺瘤结直肠肿瘤化学预防Advanced Colorectal Adenoma Advanced Adenoma Colorectal Neoplasms Chemoprevention
摘要: 进展期结直肠腺瘤(advanced colorectal adenoma, ACA)是结直肠癌(colorectal cancer, CRC)的重要前体,大多数CRC都是从腺瘤演变而来,而且ACA的恶变率更高。近年来,化学预防再一次成为热点话题,力争早期积极有效控制腺瘤的进一步发展和减少复发。目前ACA有关化学预防有非甾体抗炎药、他汀类及胆酸类药物,本文就ACA的化学预防相关药物作一综述。
Abstract: Advanced colorectal adenoma (ACA) is an important precursor of colorectal cancer. Most colorectal cancers (CRC) evolve from adenomas, and ACA has a higher rate of malignant transformation. In re-cent years, chemoprevention has once again become a hot issue, striving to actively and effectively control the further development of adenomas and reduce recurrence in the early stage. At present, there are non-steroidal anti-inflammatory drugs, statins and bile acids related to ACA chemopre-vention. This article reviews the chemoprevention related drugs of ACA.
文章引用:高建丽, 马臻棋, 王学红, 武先蓉, 曾宁. 进展期结直肠腺瘤化学预防的研究现状[J]. 临床医学进展, 2022, 12(6): 5142-5148. https://doi.org/10.12677/ACM.2022.126745

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