正念减压对肺癌患者疗效影响的系统评价

Effects of Mindfulness Decompression on Lung Cancer: A Systematic Review

摘要: 目的：分析评价正念减压对肺癌患者的疗效影响。方法：计算机检索国内外有关正念减压对肺癌患者疗效影响的随机对照试验，使用RevMan5.3软件进行统计分析。结果：共纳入20篇文献，共1587例患者。分析结果显示：应用正念减压在改善肺癌患者的焦虑[SMD = −7.79，95% CI为(−11.02, −4.57)，P < 0.00001]、抑郁[SMD = −1.10，95% CI为(−1.49, −0.71)，P < 0.00001]、癌因性疲乏[SMD = −1.35，95% CI为(−1.72, −0.98)，P < 0.00001]、自我效能[SMD = 7.04，95% CI为(6.64, 7.44)，P < 0.00001]、功能状态[MD = 7.87，95% CI为(6.29, 9.46)，P < 0.00001]和睡眠质量[MD = −2.75，95% CI为(−3.18, −2.33)，P < 0.00001]等方面优于对照组。结论：现有证据证明，正念减压作为一种心理疗法，能够减轻肺癌患者的负面情绪、减轻疲乏状态、提高自我效能和功能状态，改善睡眠质量。但是由于缺乏长期随访，正念减压对肺癌患者的长期疗效有待进一步验证。

Abstract: Objective: Analyze the intervention effect of mindfulness decompression on cancer-related fatigue and quality of life in patients with lung cancer. Method: The randomized controlled trials of mindfulness decompression on cancer-related fatigue and quality of life in lung cancer patients were searched by computer. RevMan5.3 software was used for statistical analysis. Results: A total of 20 articles were included, with a total of 1587patients. The results showed that mindfulness decompression could improve the anxiety [SMD = −7.79, 95% CI (−11.02, −4.57), P < 0.00001], depression [SMD = −1.10, 95% CI (−1.49, −0.71), P < 0.00001], cancer-related fatigue [SMD = −1.35, 95% CI (−1.72, −0.98), P < 0.00001], self-efficacy [SMD = 7.04,95% CI (6.64, 7.44), P < 0.00001], the functional status [MD = 7.87, 95% CI (6.29, 9.46), P < 0.00001] and sleep quality [MD = −2.75, 95% CI (−3.18, −2.33), P < 0.00001], which in the treatment group was better than those in the control group. Conclusion: The existing evidence shows that mindfulness decompression as a psychotherapy can reduce the negative emotions, relieve fatigue, improve self-efficacy and functional status, and improve sleep quality of patients with lung cancer. However, due to the lack of long-term follow-up, the long-term effect of mindfulness decompression on lung cancer patients needs to be further verified.