SMILE术后角膜中央后表面高度变化的远期临床研究

Long-Term Clinical Study on the Changes of Corneal Posterior Elevation after SMILE Surgery

摘要: 目的：通过研究中、高度近视患者SMILE术后远期角膜后表面高度的变化趋势，探讨SMILE手术的安全性、稳定性。方法：回顾性病例系列研究。收集2017年06月~2018年06月在我院行SMILE手术的100眼，根据术前等效球镜度将受术者分为中度近视组(−3.00~−6.00 D者，50眼)，高度近视组(近视度−6.00 D及以上者，50眼)分别于术前，术后1年、术后3年行Pentacam系统检查，比较术后各时间点后表面高度的变化趋势。结果：中度、高度近视组SMILE术后角膜后表面高度变化分别在术后1年、术后3年无统计学意义(均P > 0.05)；且中度、高度近视组组内比较在术后1年、术后3年角膜后表面高度变化均无统计学差异(均P > 0.05)；术后等效球镜在术后1年、术后3年比较均无统计学意义(均P > 0.05)。结论：SMILE术后中、高度近视角膜后表膜高度在术后1年即达到稳定状态。SMILE手术具有较高的安全性、稳定性。

Abstract: Objective: To explore the safety and stability of SMILE surgery by studying the change trend of long term corneal posterior elevation after SMILE surgery in moderate and high myopia patients. Methods: Retrospective case series study. A total of 100 eyes underwent SMILE surgery in our hos-pital from June 2017 to June 2018 were collected. According to the preoperative equivalent spher-ical lens, the subjects were divided into moderate myopia group (−3.00~−6.00 D, 50 eyes) and high myopia group (−6.00 D and above, 50 eyes). Pentacam system examination was performed 1 year and 3 years after surgery to compare the change trend of corneal posterior elevation at each time point after surgery. Results: There was no significant difference in the height of corneal posterior elevation after SMILE 1 year and 3 years in moderate and high myopia group (ALL P > 0.05). There was no significant difference in the changes of corneal posterior elevation between moderate and high myopia groups 1 year and 3 years after surgery (all P > 0.05). There was no statistical signifi-cance in postoperative equivalent spherical lens at 1 year and 3 years after surgery (all P > 0.05). Conclusion: Moderate and high myopia of corneal posterior elevation reached stable state in 1 year after SMILE surgery. SMILE surgery has high safety and stability.