姜黄素对摄食高脂饲料的血鹦鹉生长、血液及肝脏部分免疫指标的影响

Effects of Curcumin on the Growth, Blood and Some Immune Parameters of Liver in Blood Parrots Feeding on High-Fat Diets

摘要: 以初始体重(85.53 g ± 3.50 g)的血鹦鹉为研究对象，配制脂肪水平分别为8%、14%的基础饲料和高脂饲料，并在高脂饲料中分别添加100、200、400 mg/kg的姜黄素作为饲料添加剂。试验共分为5个处理，每个处理设3个平行，每个平行饲喂50尾血鹦鹉，试验周期为8周。结果显示：添加姜黄素未对试验鱼生长造成影响。血鹦鹉摄食高脂饲料后，TG、CHOL、GLU含量以及AST活性均显著升高，添加姜黄素后血鹦鹉的症状显著改善，200 mg/kg组的血脂、Glu含量以及转氨酶活性均回到对照组水平。此外，投喂高脂饲料的试验鱼的SOD和GSH-Px活性均显著低于对照组(P < 0.05)，而添加200 mg/kg以上姜黄素的各组试验鱼SOD、GSH-Px活性显著高于高脂组，MDA含量显著低于高脂组(P < 0.05)，各组的CAT活性均无显著影响(P > 0.05)。结果表明，摄食过量高脂饲料的血鹦鹉表现出氧化损伤状态，而添加适200 mg/kg姜黄素提高血鹦鹉的抗氧化力、缓解肝脏损伤。

Abstract: Blood parrots with initial body weight (85.53 g ± 3.50 g) were fed a basal diet or a high-fat diet with fat levels of 8% and 14%, respectively, and curcumin with mass fractions of 100, 200 and 400 mg/kg was added to the high-fat diet as a feed additive. The experiment was divided into 5 treatments, each with 3 parallels, and each parallel was fed to 50 blood parrots for 8 weeks. The results showed that: The addition of curcumin did not affect the growth performance of blood parrot. The symptoms of the blood parrots were significantly improved by the addition of curcumin, and the lipid, Glu and transaminase activities of the 200 mg/kg group returned to the level of the control group. In addition, the SOD and GSH-Px activities of the test fish fed high-fat diets were significantly lower than those of the control group (P < 0.05), while the SOD and GSH-Px activities of the test fish in each group supplemented with more than 200 mg/kg of curcumin were significantly higher than those of the high-fat group, and the MDA content was significantly lower than that of the high-fat group (P < 0.05), with no significant effect on CAT activity in any group (P > 0.05). The results showed that blood parrots consuming excessive high-fat diets exhibited oxidative damage, and the addition of 200 mg/kg curcumin improved the antioxidant power and alleviated liver damage in blood parrots.