天然产物抗皱活性研究进展
Research Progress of Anti-Wrinkle Activity of Natural Products
DOI: 10.12677/PI.2022.114036, PDF,   
作者: 苏志蓉, 陈亚娟*：昆明医科大学药学院，云南 昆明
关键词: 天然产物；抗皱；UVB；Natural Products； Anti-Wrinkle； UVB
摘要: 皮肤老化是人体自然状态下不可避免的过程，分为生理状态下的内在老化和外部环境损伤下的外部老化。紫外辐射是致皮肤老化最严重的外部刺激因素，皮肤暴露在紫外线辐射下会引起晒伤、免疫抑制、光老化、突变、DNA和蛋白质变性、癌症等。皱纹是皮肤老化的典型症状，由弹性丧失引起，弹性丧失与皮肤真皮组织弹性相关的胶原蛋白和弹性蛋白减少有关。我国植物资源丰富，具有广阔应用前景。近年来的大量研究证明，天然产物为抗皱活性的研究和相关产品的研发提供了新思路和新方法。本文就抗皱相关理论和多种具有抗皱活性的天然产物研究进展作一综述。
Abstract: Skin aging is an inevitable process in the natural state of a human body, which is divided into in-ternal aging under physiological state and external aging under external environmental damage. Ultraviolet radiation is the most serious external irritant causing skin aging. Skin exposure to ultraviolet radiation will cause sunburn, immunosuppression, photoaging, mutation, DNA and protein degeneration, cancer, and so on. The wrinkle is a typical symptom of skin aging, which is caused by the loss of elasticity. The loss of elasticity is related to the reduction of collagen and elastin related to the elasticity of the skin and dermal tissue. China is rich in plant resources, which is a broad research field. In recent years, a large number of studies have proved that new ideas and methods for the research of anti-wrinkle activity and the research and development of related products which come from natural plants have been formed. The relevant theories of anti-wrinkle and the research progress of many natural drugs with anti-wrinkle activity were reviewed in the present study.
文章引用：苏志蓉, 陈亚娟. 天然产物抗皱活性研究进展[J]. 药物资讯, 2022, 11(4): 278-283. https://doi.org/10.12677/PI.2022.114036

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