血清标志物与弥漫大B细胞淋巴瘤预后关系的研究进展
Research Advances in the Relationship between Serum Markers and the Prognosis of Diffuse Large B-Cell Lymphoma
DOI: 10.12677/ACM.2022.127901, PDF,    科研立项经费支持
作者: 付 滕, 杨香会, 张海亚:潍坊医学院,山东 潍坊;王彦丽, 李 丽, 接贵涛*:临沂市中心医院血液科,山东 临沂
关键词: 弥漫大B细胞淋巴瘤血清标志物预后Diffuse Large B-Cell Lymphoma Serum Markers Prognosis
摘要: 弥漫大B细胞淋巴瘤是最常见的非霍奇金淋巴瘤,具有高度异质性。利妥昔单抗时代,患者的治愈率得到很大的提高,但仍有部分患者出现耐药或早期复发,传统的预后评估手段在新时期受到了极大的挑战。近些年,血清标志物因其易获得、便于动态评估和价格低廉等优势,在DLBCL的预后评估中的作用受到关注。本文就初诊及治疗过程中患者的外周血淋巴细胞/单核细胞比值(LMR)、β2微球蛋白(β2MG)、红细胞沉降率(ESR)、红细胞分布宽度(RDW)做一综述。
Abstract: Diffuse large B-cell lymphoma is the most common non-Hodgkin lymphoma and is highly heteroge-neous. In the era of rituximab, the cure rate of patients has been greatly improved, but some pa-tients still develop drug resistance or early recurrence, and the traditional prognostic evaluation methods have been greatly challenged in the new period. In recent years, the role of serum markers in the prognosis assessment of DLBCL has attracted attention because of its advantages of easy availability, easy dynamic assessment and low price. In this paper, the peripheral blood lympho-cyte/monocyte ratio (LMR), β2 microglobulin (β2MG), erythrocyte sedimentation rate (ESR), and red blood cell distribution width (RDW) of patients during initial diagnosis and treatment are reviewed.
文章引用:付滕, 杨香会, 张海亚, 王彦丽, 李丽, 接贵涛. 血清标志物与弥漫大B细胞淋巴瘤预后关系的研究进展[J]. 临床医学进展, 2022, 12(7): 6239-6245. https://doi.org/10.12677/ACM.2022.127901

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