红细胞分布宽度在骨科中的应用进展
Application of RDW in Orthopedic Disease
摘要: 红细胞分布宽度(red cell distribution width, RDW)是一个反映循环红细胞大小异质性的参数。多项研究表明，RDW水平在多种骨科疾病中具有一定的临床意义，如类风湿性关节炎(rheumatoid ar-thritis, RA)，强直性脊柱炎(ankylosing spondylitis, AS)，骨关节炎(osteoarthritis, OA)，髋部骨折以及关节置换术。该文将重点对RDW在骨科疾病中的应用进展进行综述。
Abstract: Red cell distribution width (RDW) is a parameter that reflects the size heterogeneity of circulating red blood cells. Many studies have shown that RDW levels have certain clinical significance in vari-ous orthopedic diseases, such as rheumatoid arthritis (RA), ankylosing spondylitis (AS), osteoar-thritis (OA), hip fractures, and joint replacements. This review focuses on the application of RDW in orthopedic disease.
文章引用：饶舜. 红细胞分布宽度在骨科中的应用进展[J]. 临床医学进展, 2022, 12(7): 6616-6620. https://doi.org/10.12677/ACM.2022.127955

参考文献

[1] Clarke, K., Sagunarthy, R. and Kansal, S. (2008) RDW as an Additional Marker in Inflammatory Bowel Disease/ Undif-ferentiated Colitis. Digestive Diseases and Sciences, 53, 2521-2523. [Google Scholar] [CrossRef] [PubMed]
[2] Sousa, R., Goncalves, C., Guerra, I.C., et al. (2016) Increased Red Cell Distribution Width in Fanconi anemia: A Novel Marker of Stress Erythropoiesis. Orphanet Journal of Rare Diseases, 11, 102. [Google Scholar] [CrossRef] [PubMed]
[3] Wu, T.-T., Zheng, Y.-Y., Hou, X.-G., et al. (2019) Red Blood Cell Distribution Width as Long-Term Prognostic Markers in Patients with Coronary Artery Disease Undergoing Percu-taneous Coronary Intervention. Lipids in Health and Disease, 18, 140. [Google Scholar] [CrossRef] [PubMed]
[4] 石晶, 焦军东. 红细胞分布宽度在慢性肾脏病诊疗中的应用进展[J]. 中国中西医结合肾病杂志, 2022, 23(1): 90-91.
[5] Wang, Y., Zhou, Y., Zhou, K., et al. (2020) Prognostic Value of Pre-Treatment Red Blood Cell Distribution Width in Lung Cancer: A Meta-Analysis. Biomarkers, 25, 241-247. [Google Scholar] [CrossRef] 
[6] Daghestani, H.N. and Kraus, V.B. (2015) Inflammatory Biomarkers in Osteoarthritis. Osteoarthritis Cartilage, 23, 1890-1896. [Google Scholar] [CrossRef] [PubMed]
[7] Okamoto, K., Nakashima, T., Shinohara, M., et al. (2017) Osteo-immunology: The Conceptual Framework Unifying the Immune and Skeletal Systems. Physiological Reviews, 97, 1295-1349. [Google Scholar] [CrossRef] [PubMed]
[8] Tecer, D., Sezgin, M., Kanik, A., et al. (2016) Can Mean Platelet Volume and Red Blood Cell Distribution Width Show Disease Activity in Rheumatoid Arthritis? Bi-omarkers in Medicine, 10, 967-974. [Google Scholar] [CrossRef] [PubMed]
[9] Yunchun, L., Yue, W., Jun, F.Z., et al. (2016) Clinical Significance of Red Blood Cell Distribution Width and Inflammatory Factors for the Disease Activity in Rheumatoid Arthritis. Clini-cal Laboratory, 62, 2327-2331. [Google Scholar] [CrossRef] 
[10] Lin, F., Wang, X., Liang, Y., et al. (2018) Red Blood Cell Dis-tribution Width in Rheumatoid Arthritis, Ankylosing Spondylitis and Osteoarthritis: True Inflammatory Index or Effect of Anemia? Annals of Clinical & Laboratory Science, 48, 301-307.
[11] Horta-Baas, G. and Romero-Figueroa, M.D.S. (2019) Clinical Utility of Red Blood Cell Distribution Width in Inflammatory and Non-Inflammatory Joint Diseases. In-ternational Journal of Rheumatic Diseases, 22, 47-54. [Google Scholar] [CrossRef] 
[12] 董晓玉, 贾晓益, 夏江莉, 许丹丹, 王席. 红细胞体积分布宽度在类风湿关节炎诊断中的临床价值[J]. 中国临床保健杂志, 2022, 25(1): 86-90.
[13] Perrotta, F.M., Scriffignano, S., Ciccia, F., et al. (2022) Therapeutic Targets for Ankylosing Spondylitis—Recent Insights and Future Prospects. Open Access Rheumatology, 14, 57-66. [Google Scholar] [CrossRef] 
[14] Peng, Y.-F., Zhang, Q., Cao, L., et al. (2014) Red Blood Cell Distribution Width: A Potential Maker Estimating Disease Activity of Ankylosing Spondy-litis. International Journal of Clinical and Experimental Medicine, 7, 5289-5295.
[15] Gorial, F.I. and Hassan, A.M. (2018) Diagnostic Performance of Red Cell Distribution Width in Adult Iraqi Patients with Ankylosing Spondylitis. Ar-thritis, 2018, Article ID: 2904694. [Google Scholar] [CrossRef] [PubMed]
[16] Deng, J., Xu, S., Gao, X., et al. (2021) Red Cell Distribution Width and Mean Platelet Volume in Patients with Ankylosing Spondylitis: A Systematic Review and Meta-Analysis. Journal of Clinical Rheumatology, 27, 292-297. [Google Scholar] [CrossRef] 
[17] Song, G.G. and Lee, Y.H. (2020) Red Cell Distribution Width, Platelet-to-Lymphocyte Ratio, and Mean Platelet Volume in Ankylosing Spondylitis and Their Correlations with Inflammation: A Meta-Analysis. Modern Rheumatology, 30, 894-899. [Google Scholar] [CrossRef] [PubMed]
[18] Bozan, N., Alpayci, M., Aslan, M., et al. (2016) Mean Platelet Volume, Red Cell Distribution Width, Platelet-to- Lymphocyte and Neutrophil-to-Lymphocyte Ratios in Patients with Ankylosing Spondylitis and Their Relationships with High-Frequency Hearing Thresholds. European Archives of Oto-Rhino-Laryngology, 273, 3663-3672. [Google Scholar] [CrossRef] [PubMed]
[19] Hao, X., Li, D., Wu, D., et al. (2017) The Relationship between Hematological Indices and Autoimmune Rheumatic Diseases (ARDs), a Meta-Analysis. Scientific Reports, 7, Article No. 10833. [Google Scholar] [CrossRef] [PubMed]
[20] Berenbaum, F. (2013) Osteoarthritis as an Inflammatory Disease (Osteoarthritis Is Not Osteoarthrosis!). Osteoarthritis Cartilage, 21, 16-21. [Google Scholar] [CrossRef] [PubMed]
[21] 赵娜, 康利宝. 红细胞分布宽度指标预测骨关节炎炎症进程的临床价值[J]. 现代检验医学杂志, 2019, 34(4): 91-95.
[22] 孙泰, 卜素, 黄开泉, 刘漪, 钱琤. 红细胞分布宽度和中性粒细胞/淋巴细胞比值与骨关节炎疾病活动的相关性分析[J]. 蚌埠医学院学报, 2016, 41(7): 945-947.
[23] Bhandari, M. and Swiontkowski, M. (2017) Management of Acute Hip Fracture. The New England Journal of Medicine, 377, 2053-2062. [Google Scholar] [CrossRef] 
[24] Zehir, S., Sipahioglu, S., Ozdemir, G., et al. (2014) Red Cell Distribution Width and Mortality in Patients with Hip Fracture Treated with Partial Prosthesis. Acta Orthopaedica et Traumatologica Turcica, 48, 141-146. [Google Scholar] [CrossRef] 
[25] Marom, O., Paz, I., Topaz, G., et al. (2022) Red Cell Distribution Width—A Mortality Predictor in Older Adults with Proximal Femoral Fracture. Archives of Gerontology and Geriatrics, 100, Article ID: 104623. [Google Scholar] [CrossRef] [PubMed]
[26] Hamdan, M., Haddad, B.I., Jabaiti, M., et al. (2021) Does Red Cell Distribution Width Predict Hip Fracture Mortality among the Arab Population? A Single-Center Retrospective Co-hort Study. International Journal of General Medicine, 14, 10195-10202. [Google Scholar] [CrossRef] 
[27] Learmonth, I.D., Young, C. and Rorabeck, C. (2007) The Operation of the Century: Total Hip Replacement. The Lancet, 370, 1508-1519. [Google Scholar] [CrossRef] 
[28] Falck-Ytter, Y., Francis, C.W., Johanson, N.A., et al. (2012) Prevention of VTE in Orthopedic Surgery Patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest, 141, e278S-e325S. [Google Scholar] [CrossRef] [PubMed]
[29] Xu, Z., Li, L., Shi, D., et al. (2015) The Level of Red Cell Distribution Width Cannot Identify Deep Vein Thrombosis in Patients Undergoing Total Joint Arthroplasty. Blood Coagulation & Fibrinolysis, 26, 298-301. [Google Scholar] [CrossRef] 
[30] Aali-Rezaie, A., Alijanipour, P., Shohat, N., et al. (2018) Red Cell Distribution Width: An Unacknowledged Predictor of Mortality and Adverse Outcomes Following Revision Arthroplasty. The Journal of Arthroplasty, 33, 3514-3519. [Google Scholar] [CrossRef] [PubMed]
[31] Casp, A.J., Sequeira, S.B., Kew, M.E., et al. (2020) Red Cell Dis-tribution Width as a Novel Predictor of Mortality and Complications after Primary Shoulder Arthroplasty. Journal of the American Academy of Orthopaedic Surgeons, 28, 802-807. [Google Scholar] [CrossRef] 

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