颅内桥小脑角区恶性黑色素瘤1例并文献复习

Malignant Melanoma in Cerebellopontine Angle: A Case Report and Literature Review

摘要: 原发性颅内黑色素瘤是一种极为罕见的脑部病变，约占所有黑色素瘤病例的1%。继发性颅内恶性黑色素瘤大多原发于体表皮肤恶性黑色素瘤，且颅内继发恶性黑色素瘤一般位于大脑实质内。颅内黑色素瘤恶性程度高，生长速度快，浸润性生长范围广泛，手术不易彻底切除，术后易复发，预后极差，目前能有效控制颅内黑色素瘤的治疗手段有限。发生于颅内桥小脑角区的恶性黑色素瘤较少报道，本文报道一例桥小脑角区恶性黑色素瘤，血供丰富，呈浸润性生长，与周围组织粘连紧密，手术切除复杂，希望为颅内桥小脑角区恶性黑色素瘤提供更多治疗参考。

Abstract: Primary intracranial melanoma is an extremely rare brain lesion that accounts for about 1% of all melanoma cases. Secondary intracranial malignant melanoma mostly originates from superficial cutaneous malignant melanoma, and the secondary intracranial malignant melanoma is usually lo-cated in the brain parenchyma. Intracranial melanoma has a high degree of malignancy, fast growth rate, and a wide range of invasive growth. It is not easy to be completely resected by surgery, and postoperative recurrence is easy, with a poor prognosis. Currently, there are limited therapeutic methods that can effectively control intracranial melanoma. Malignant melanoma occurring in the intracranial pontine Angle is rarely reported. This paper reports a case of malignant melanoma in cerebellopontine angle region, which has abundant blood supply, infiltrative growth, close adhesion with surrounding tissues, and complex surgical resection. It is hoped to provide more treatment references for malignant melanoma in cerebellopontine angle region.