紫菀、蜜紫菀及其配方颗粒的薄层色谱研究

TLC Study on Aster, Honey Aster and Its Formula Granules

摘要: 紫菀来源于菊科植物紫菀Aster tataricus L. f.的干燥根和根茎。紫菀的化学成分包括萜类、皂苷类、黄酮等，具有镇咳、祛痰、平喘等多种功效，临床应用范围较广。近年来，中药配方颗粒逐渐取代传统饮片的应用，中药配方颗粒的质量控制应该得到重视。因此本研究在2020版《中国药典》项下紫菀的薄层色谱条件的基础上，优化其薄层色谱展开条件，研究紫菀与蜜紫菀及蜜紫菀配方颗粒的薄层色谱的相关性。优化后的薄层色谱鉴别方法简便、快速、信息丰富，能评价紫菀与蜜紫菀及蜜紫菀配方颗粒三者之间成分相关性，同时可为紫菀与蜜紫菀及蜜紫菀配方颗粒的质量控制提供参考。

Abstract: Aster is derived from the dried root and rhizome of Aster tataricus L. f., the Asteraceae plant. The chemical constituents of Aster include terpenoids, saponins, flavonoids and so on. It has the functions of antitussive, expectorant, antiasthmatic and so on, and has a wide range of clinical applications. In recent years, traditional Chinese medicine granule has gradually replaced the application of traditional decoction pieces, and the quality control of traditional Chinese medicine granule should be paid attention to. Therefore, based on the TLC conditions of Aster in Chinese Pharmacopoeia 2020 edition, this study optimized the TLC development conditions of Aster, and studied the TLC correlation between Aster and honey Aster and honey Aster formula granules. The optimized TLC identification method is simple, rapid and informative. It can be used to evaluate the correlation between Aster and honey Aster and honey Aster formula granules, and provide a reference for the quality control of Aster, honey Aster and honey Aster formula granules.