心脏磁共振成像在高原性心脏病的结构和功能定量评价中的研究进展

Research Progress in Quantitative Evaluation of Structure and Function by Cardiac Magnetic Resonance Imaging in High Altitude Heart Disease

摘要: 高原性心脏病(high altitude heart disease, HAHD)是机体长期对高海拔低压缺氧环境下产生的一系列生理病理反应，导致以循环系统障碍为代表的疾病。HAHD是慢性高原病的一种，主要特征是肺动脉高压，可同时伴右心室肥厚及右心功能不全。心脏磁共振成像(cardiac magnetic resonance, CMR)具有高分辨率、无创无电离辐射、多参数成像等特点，能够对心脏结构、功能、灌注、代谢、心肌组织特征改变等做出“一站式”评价，在心脏疾病的早期诊断、危险分层、预后评价中具有独特价值，已经成为诊断心血管疾病的重要手段，有着深远广阔的应用前景及重大临床意义，因此本文对CMR在HAHD患者心脏结构和功能定量评价中的研究进展进行综述。

Abstract: High altitude heart disease (HAHD) is a series of physiological and pathological reactions caused by the body under the environment of high altitude, low pressure and hypoxia for a long time, leading to diseases represented by circulatory system disorders. HAHD is a type of chronic mountain sick-ness characterized by pulmonary hypertension, accompanied by right ventricular hypertrophy and right heart dysfunction. Cardiac magnetic resonance (CMR) with high resolution, noninvasive no ionizing radiation, multi-parameter imaging characteristics, such as the ability to cardiac structure, function, perfusion, metabolism, changes in myocardial tissue characteristics such as a “one-stop” assessment, in the early diagnosis and risk stratification of heart disease, has the unique value in the assessment of prognosis, has become an important means of diagnosis of cardiovascular disease. It has far-reaching and broad application prospects and significant clinical significance. Therefore, this paper reviews the research progress of CMR in the quantitative evaluation of cardiac structure and function in HAHD patients.