TFRC在妇科肿瘤中的研究进展
Research Progress of TFRC in Gynecological Tumors
DOI: 10.12677/ACM.2022.1281014, PDF,   
作者: 杨克鑫*:青岛大学医学院妇产科学,山东 青岛;徐冠华:吉林大学第一临床医学院呼吸与危重症学,吉林 长春
关键词: TFRC妇科肿瘤研究进展TFRC Gynecologic Tumors Research Advances
摘要: 转铁蛋白受体(Transferrin Receptor, TFRC)是细胞摄取铁的重要膜蛋白,也是铁进入细胞的限制步骤,对防止细胞内铁超载至关重要。研究发现,TFRC在多种肿瘤细胞中均有异常表达,并参与肿瘤的发生和发展过程。在这篇综述中,我们讨论了TFRC在部分妇科肿瘤中的最新研究进展,并探索TFRC在妇科肿瘤中的应用前景。
Abstract: TFRC is an important membrane protein for cell uptake of iron, and it is also a restrictive step for iron to enter the cell, which is essential to prevent intracellular iron overload. The study found that TFRC is abnormally expressed in a variety of tumor cells and is involved in the occurrence and de-velopment of tumors. In this review, we discuss the latest research advances of TFRC in some gyne-cological tumors and explore the application prospects of TFRC in gynecological tumors.
文章引用:杨克鑫, 徐冠华. TFRC在妇科肿瘤中的研究进展[J]. 临床医学进展, 2022, 12(8): 7047-7052. https://doi.org/10.12677/ACM.2022.1281014

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