长期腹膜透析患者伴下肢动脉硬化闭塞症一例并文献复习
Long-Term Peritoneal Dialysis Patient with Lower Limb Atherosclerotic Occlusive Disease: A Case Report and Literature Review
DOI: 10.12677/ACM.2022.1281017, PDF,   
作者: 孔 洁*:济宁医学院临床医学院,山东 济宁;魏明明#, 孟 雪, 李新建:济宁医学院附属医院肾内科,山东 济宁
关键词: 腹膜透析外周动脉疾病终末期肾病Peritoneal Dialysis Peripheral Arterial Disease End-Stage Renal Disease
摘要: 目的:通过1例腹膜透析患者合并下肢动脉闭塞的病例,探讨该病例诊治线索以及治疗时机。方法:回顾性分析我院1例腹膜透析患者合并下肢动脉闭塞临床表现、诊治思路、治疗结局,并进行相关文献复习。结果:该例患者因感染、合并症多,最终死亡。结论:因严重肢体缺血接受下肢动脉闭塞干预且同时患有CKD/ESRD的患者发生大截肢和早期死亡的风险增加。
Abstract: Objective: A case of a peritoneal dialysis patient with lower limb arterial occlusion is used to discuss the clues to the diagnosis and management of the case and the timing of treatment. Methods: A ret-rospective analysis of the clinical manifestations, diagnostic ideas and treatment outcomes of a case of combined lower limb arterial occlusion in a peritoneal dialysis patient at our hospital, and a re-view of the relevant literature. Results: Patients due to numerous infections, comorbidities had died eventually. Conclusion: Patients undergoing lower limb arterial occlusion intervention for severe limb ischaemia who also have CKD/ESRD are at increased risk of major amputation and early death.
文章引用:孔洁, 魏明明, 孟雪, 李新建. 长期腹膜透析患者伴下肢动脉硬化闭塞症一例并文献复习[J]. 临床医学进展, 2022, 12(8): 7065-7070. https://doi.org/10.12677/ACM.2022.1281017

参考文献

[1] Sheikh, A.B., Na Gpal, S., et al. (2021) Systematic Review and Meta Analysis of Outcomes of Lower Extremity Periph-eral Arterial Interventions in Patients with and without Chronic Kidney Disease or End Stage Renal Disease. Journal of Vascular Surgery, 73, 331-340. [Google Scholar] [CrossRef] [PubMed]
[2] Lee, M.S., Rha, S.W., Han, S.K., et al. (2015) Comparison of Diabetic and Non-Diabetic Patients Undergoing Endovascular Revascularization for Peripheral Arterial Disease. Journal of Invasive Cardiology, 27, 167-171.
[3] Barnes, J.A., Eid, M.A., Creager, M.A., et al. (2020) Epidemiology and Risk of Amputation in Patients with Diabetes Mellitus and Peripheral Artery Disease. Arteriosclerosis Thrombosis and Vascular Biology, 40, 1808-1817. [Google Scholar] [CrossRef
[4] Conte, M.S., Bradbury, A.W., Kolh, P., et al. (2019) Global Vascular Guidelines on the Management of Chronic Limb-Threatening Ischemia. Journal of Vascular Surgery, 69, s3-s125. [Google Scholar] [CrossRef] [PubMed]
[5] Sicard, G.A. (2018) Rutherford’s Vascular Surgery and Endovascular Therapy. Journal of Vascular Surgery, 68, 1611-1612. [Google Scholar] [CrossRef
[6] Son, B.-K., et al. (2006) Statins Protect Human Aortic Smooth Muscle Cells from Inorganic Phosphate-Induced Calcification by Restoring Gas6-Axl Survival Pathway. Circulation Research, 98, 1024-1031. [Google Scholar] [CrossRef
[7] Raikou, V.D. and Kyriaki, D. (2019) Factors Related to Peripheral Arterial Disease in Patients Undergoing Hemodialysis: The Potential Role of Monocyte Chemoattractant Protein-1. Hypertension Research, 42, 1528-1535. [Google Scholar] [CrossRef] [PubMed]
[8] Pletinck, A., Glorieux, G., Schepers, E., et al. (2013) Pro-tein-Bound Uremic Toxins Stimulate Crosstalk between Leukocytes and Vessel Wall. Journal of the American Society of Nephrology, 24, 1981-1994. [Google Scholar] [CrossRef
[9] Mozar, A., Haren, N., Chasseraud, M., et al. (2010) High Extra-cellular Inorganic Phosphate Concentration Inhibits RANK-RANKL Signaling in Osteoclast-Like Cells. Journal of Cel-lular Physiology, 215, 47-54. [Google Scholar] [CrossRef] [PubMed]
[10] Aboyans, V., Ricco, J.B., Bartelink, M.E., et al. (2018) Editor’s Choice-2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in Collaboration with the European Society for Vascular Surgery (ESVS). European Journal of Vascular and Endovascular Surgery: The Official Journal of the European Society for Vascular Surgery, 55, 305-368. [Google Scholar] [CrossRef] [PubMed]
[11] Garimella, P.S. and Hirsch, A.T. (2014) Peripheral Artery Disease and Chronic Kidney Disease: Clinical Synergy to Improve Outcomes. Advances in Chronic Kidney Disease, 21, 460-471. [Google Scholar] [CrossRef] [PubMed]
[12] Dawson, D.B., Telles-Garcia, N.A., Atkins, J.L., et al. (2021) End-Stage Renal Disease Patients Undergoing Angioplasty and Bypass for Critical Limb Ischemia Have Worse Out-comes Compared to Non-ESRD Patients: Systematic Review and Meta-Analysis. Systematic Review and Meta-Analysis, 98, 297-307. [Google Scholar] [CrossRef] [PubMed]
[13] Kayssi, A., Oreopoulos, G., et al. (2016) Drug-Eluting Bal-loon Angioplasty versus Uncoated Balloon Angioplasty for Peripheral Arterial Disease of the Lower Limbs. Cochrane Database of Systematic Reviews, 63, 105S-106S. [Google Scholar] [CrossRef
[14] Fakhry, F., Fokkenrood, H.J., Spronk, S., et al. (2018) Endovascu-lar Revascularisation versus Conservative Management for Intermittent Claudication. Cochrane Database of Systematic Reviews, 3, 64-65. [Google Scholar] [CrossRef
[15] Mensah, G.A., Roth, G.A., Ademi, Z., et al. (2020) Glob-al Burden of Cardiovascular Diseases and Risk Factors, 1990-2019. Journal of the American College of Cardiology, 76, 2982-3021.
[16] O’Hare, A.M. (2004) Postoperative Mortality after Nontraumatic Lower Extremity Amputation in Pa-tients with Renal Insufficiency. Journal of the American Society of Nephrology, 15, 427-434. [Google Scholar] [CrossRef