基于Au/BiOI的光电化学传感器对血清素超灵敏检测
Au/BiOI Based Photoelectrochemical Sensor for Ultra-Sensitive Detection of 5-Hydroxytryptamine
摘要: 目的：本研究通过水热法制备了尺寸均一的金纳米粒子以及碘氧化铋(BiOI)纳米花，将二者复合后(Au/BiOI)用于血清素(5-hydroxytryptamine, 5-HT)的光电化学检测。Au/BiOI检测5-HT时有显著的光电流响应，这主要是由于在可见光照下，BiOI产生光生电子(e−)-空穴(h+)对，可以吸附更多的5-HT至电极表面并氧化，增加光电流；而Au纳米粒子的局域表面等离子共振效应可以增强光电流响应；此外，Au较强的导电能力可以阻止电子–空穴对的复合，进一步提高光电流，最终实现对5-HT的超灵敏性检测。该光电传感器检测5-HT时的浓度范围在0.25~20 μM之间，检出限为0.07 μM，表明Au/BiOI对5-HT具有较好的光电化学检测效果。该光电化学传感器还拥有稳定性好和灵敏度高等优点，期待其在生物小分子的检测中具有广阔的应用前景。
Abstract: Purpose: In this study, homogeneous Au NPs and BiOI nanoflowers were synthesized by hydrothermal method and the Au/BiOI composite was applied to the specific photochemical detection of 5-hydroxytryptamine (5-HT). Au/BiOI based photoelectrochemical (PEC) sensor has a significant photocurrent response for detection of 5-HT, which is mainly due to the photogenerated electron (e−) hole (h+) pair generated by BiOI under visible light irradiation, which can adsorb more 5-HT to the electrode surface and oxidize 5-HT, increasing the photocurrent. Au NPs has strong effect of local surface plasmon resonance (LSPR) effect, which can improve the PEC response. Furthermore, Au NPs has good electrical conductivity, which will prevent the recombination of electron-hole pairs, further increases the photocurrent response, and finally realizes the ultra-sensitive detection of 5-HT. The concentration range of the photochemical sensor for AC detection was between 0.25 μM and 20 μM, the detection limit was 0.07 μM, indicating that Au/BiOI had a good performance towards 5-HT detection. The PEC sensor has good stability and high sensitivity; it is expected to have a broad application prospect in small biological molecules.
文章引用：郭旭, 卑佳丽, 范春, 董一鑫, 梁海贤, 王锦, 陈婷婷. 基于Au/BiOI的光电化学传感器对血清素超灵敏检测[J]. 分析化学进展, 2022, 12(3): 196-205. https://doi.org/10.12677/AAC.2022.123025

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