肺原发性骨外尤因肉瘤1例

Primary Extraosseous Ewing’s Sarcoma of Lung: A Case Report

摘要: 目的：探讨肺原发性骨外尤因肉瘤的临床表现、临床病理特征、诊断、鉴别诊断及治疗。方法：回顾性分析1例发生于肺的尤因肉瘤，对组织进行病理学检查及相关实验室指标的检查，结合临床及影像学资料，并结合相关文献对该疾病进行分析。结果：患儿，女，14岁，因“突发右侧胸痛半天”入院，入院后积极完善相关检查，最后诊断为尤因肉瘤明确。患儿入院后经过治疗临床症状好转，经我院多科室会诊后，建议在有条件的专科医院进一步诊治。结论：发生于肺的骨外尤因肉瘤非常罕见，确诊主要依靠病理检查，结合影像学及其它如免疫表型和分子检测等有助于诊断，应加强对该疾病免疫表型及病理特征的认识，避免误诊或漏诊影响后续治疗。

Abstract: Objective: To investigate the clinical manifestations, clinicopathological features, diagnosis and treatment of pulmonary primary extraosseous Ewing’s sarcoma. Methods: A case of pulmonary Ewing’s sarcoma was retrospectively analyzed. The pathological examination of the tissues and re-lated laboratory indicators were carried out, and the disease was analyzed in combination with clinical and imaging data and related literatures. Results: The patient, female, 14 years old, was admitted to hospital due to “sudden right chest pain for half a day”. After admission, relevant ex-aminations were actively improved, and ewing sarcoma was finally diagnosed. After treatment, the patient’s clinical symptoms improved. After multi-department consultation in our hospital, further diagnosis and treatment were recommended in qualified specialized hospitals. Conclusion: Ex-traosinal Ewing’s sarcoma occurring in lung is very rare, and the diagnosis mainly depends on pathological examination. Imaging and other immunophenotypes and molecular detection are helpful for diagnosis. It is necessary to strengthen the understanding of the immunophenotype and pathological characteristics of this disease, so as to avoid misdiagnosis or missed diagnosis affecting subsequent treatment.