阻塞性睡眠呼吸暂停综合征与动脉粥样硬化研究进展
Research Progress of Obstructive Sleep Apnea Syndrome and Atherosclerosis
摘要: 研究发现睡眠呼吸暂停综合征与动脉粥样硬化疾病存在相关性，近期研究发现睡眠呼吸暂停综合征导致的慢性间歇性缺氧、高碳酸血症、炎症因子释放、交感神经激活等机制参与了动脉粥样硬化的血管内皮受损、血脂代谢异常、中性粒细胞及淋巴细胞的趋化及黏附全过程，从而诱发或加重动脉粥样硬化。本文就睡眠呼吸暂停综合征可能导致或加重动脉粥样硬化的机制进一步阐述。
Abstract: Studies have found that obstructive sleep apnea hypopnea syndrome is related to atherosclerotic diseases. Recent studies have found that mechanisms such as chronic intermittent hypoxia, hyper-capnia, inflammatory factor release, sympathetic nerve activation caused by obstructive sleep ap-nea hypopnea syndrome are involved in the whole process of vascular endothelial damage, abnor-mal lipid metabolism, neutrophil and lymphocyte chemotaxis and adhesion of atherosclerosis, thus inducing or aggravating atherosclerosis. This article further expounds the mechanism that obstruc-tive sleep apnea hypopnea syndrome may cause or aggravate atherosclerosis.
文章引用：游振宁, 杨青岩. 阻塞性睡眠呼吸暂停综合征与动脉粥样硬化研究进展[J]. 临床医学进展, 2022, 12(8): 7284-7291. https://doi.org/10.12677/ACM.2022.1281052

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