VEGF通路抑制剂相关肾损伤研究新进展
Advances in Research on VEGF Pathway Inhibitors Related Renal Injury
DOI: 10.12677/ACM.2022.1281077, PDF,   
作者: 唐文武*, 谢席胜#:川北医学院第二临床学院(南充市中心医院)肾内科,四川 南充
关键词: VEGF通路抑制剂蛋白尿高血压血栓性微血管病急性肾损伤VEGF Pathway Inhibitor Proteinuria Hypertension Thrombotic Microangiopathy Acute Kidney In-jury
摘要: 随着接受VEGF通路抑制剂治疗恶性肿瘤患者的不断增加,该药引发的相关肾脏损伤也越来越得到重视。靶向药物肾损伤的有效预防、早期识别及管理是肾内科及肿瘤科医生共同面临的挑战。本文综述了VEGF通路抑制剂所致蛋白尿、高血压、血栓性微血管病和急性肾损伤的相关临床诊治进展,为临床规范化诊疗奠定基础。
Abstract: With the increasing number of patients receiving VEGF pathway inhibitors in the treatment of ma-lignant tumors, more and more attention has been paid to the related renal damage caused by this drug. Effective prevention, early identification and management of targeted drug renal injury are common challenges for physicians in nephrology and oncology. This paper reviews the progress in clinical diagnosis and treatment of proteinuria, hypertension, thrombotic microvascular disease and acute kidney injury caused by VEGF pathway inhibitors, which lays the foundation for stand-ardized clinical diagnosis and treatment.
文章引用:唐文武, 谢席胜. VEGF通路抑制剂相关肾损伤研究新进展[J]. 临床医学进展, 2022, 12(8): 7462-7472. https://doi.org/10.12677/ACM.2022.1281077

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