正五聚蛋白3与肺部感染相关性研究新进展
Recent New Progress in Research on the Correlation between Pentraxin 3 and Pulmonary Infection
DOI: 10.12677/ACM.2022.1281079, PDF,   
作者: 董艳芳：延安大学，榆林市第一医院，陕西 榆林
关键词: PTX3；肺部感染；先天免疫；肺损伤；Pentraxin 3； Pulmonary Infection； Congenital Immunity； Injury of Lungs
摘要: 肺作为人体最大的呼吸器官与外界进行气体交换，可直接与病原体及其他有害刺激性气体接触。肺部感染作为呼吸系统常见病、多发病，近些年其发病率及死亡率上升趋势显著。可溶性识别分子正五聚蛋白3 (PTX3)是早期发现的一种急性期反应蛋白，是天然免疫反应中体液反应的重要组成部分，是机体抵御外界微生物入侵的第一道防线，在预防肺部感染中发挥重要作用。近年来也有研究显示，PTX3在肺部感染治疗中发挥一定作用。本文将对PTX3在肺部感染研究中新进展作一综述。
Abstract: As the largest respiratory organ in the human body, the lungs exchange gas with the outside world and can directly contact pathogens and other harmful irritating gases. Pulmonary infection is a common and frequently-occurring disease of the respiratory system, and its morbidity and mortal-ity have increased significantly in recent years. The soluble recognition molecule Pentraxin 3 (PTX3) is an acute phase response protein discovered early. It is an important part of the humoral response in the natural immune response and the body’s first line of defense against the invasion of external microorganisms, playing an important role in infection. In recent years, studies have also shown that PTX3 plays a role in the treatment of pulmonary infections. This article will review the new progress of PTX3 in pulmonary infection research.
文章引用：董艳芳. 正五聚蛋白3与肺部感染相关性研究新进展[J]. 临床医学进展, 2022, 12(8): 7479-7484. https://doi.org/10.12677/ACM.2022.1281079

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