高尿酸血症及其对红细胞的影响
Hyperuricemia and Its Effect on Erythrocytes
DOI: 10.12677/ACM.2022.1281086, PDF,   
作者: 邹 静:青海大学研究生院,青海 西宁;苏 娟*:青海大学附属医院风湿科,青海 西宁
关键词: 高尿酸血症氧化应激红细胞Hyperuricemia Oxidative Stress Erythrocytes
摘要: 近年来,高尿酸血症的患病率在世界范围内不断上升。虽然高尿酸血症的发病机制复杂多样,但已有相关研究表明,高尿酸血症可参与多种生物学过程和信号通路。在本篇综述中,我们回顾了尿酸的病理生理学、高尿酸血症发病机制及治疗方案。此外,我们还讨论了高尿酸血症对红细胞可能产生的影响以及可能的作用机制,以便提供更有效的临床干预。
Abstract: In recent years, the prevalence of hyperuricemia has been increasing worldwide. Although the pathogenesis of hyperuricemia is complex and diverse, relevant studies have shown that hyperu-ricemia can participate in a variety of biological processes and signaling pathways. In this review, we review the pathophysiology, pathogenesis, and treatment of uric acid. In addition, we also dis-cuss the possible effects of hyperuricemia on RBC and the possible mechanisms of action, in order to provide more effective clinical interventions.
文章引用:邹静, 苏娟. 高尿酸血症及其对红细胞的影响[J]. 临床医学进展, 2022, 12(8): 7529-7534. https://doi.org/10.12677/ACM.2022.1281086

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