超声引导下细针穿刺细胞学诊断对不同大小甲状腺结节的诊断价值

Diagnostic Value of Ultrasound-Guided Fine Needle Aspiration Cytology for Thyroid Nodules of Different Sizes

摘要: 目的：分析甲状腺不同大小结节进行超声引导下细针穿刺细胞学诊断(US-FNA)的阳性率和准确率。方法：研究我院2020年04月~2021年08月119例甲状腺结节患者，均进行US-FNA检查，根据结节大小不同将其分为三组，A组(结节直径 ≤ 5 mm，16例)、B组(结节直径6~10 mm，40例)、C组(结节直径 ≥ 10 mm，63例)，以手术病理结果为金标准，分析A、B、C三组结节阳性检出率及诊断的准确率。结果：超声诊断US-FNA诊断阳性率为38.66%，与病理诊断阳性率48.74%对比无显著差异，无统计学意义(P > 0.05)。US-FNA穿刺准确率在B组(结节直径6~10 mm)最高为95.00%，与A组(结节直径 ≤ 5 mm)对比差异显著，具有统计学意义(P < 0.05)，与C组(结节直径 ≥ 10 mm)对比差异不具有统计学意义(P > 0.05)。结论：超声引导下细针穿刺细胞学诊断对不同大小甲状腺结节均有较高临床应用价值。

Abstract: Objective: To analyze the positive rate and accuracy rate of ultrasound-guided fine needle aspira-tion cytology (US-FNA) for thyroid nodules of different sizes. Methods: From April 2020 to August 2021, 119 patients with thyroid nodules underwent fine needle aspiration cytology under the guidance of ultrasound. They were divided into three groups according to the size of the nodules. Group A (nodule diameter ≤ 5 mm, 16 cases), Group B (nodule diameter 6~10 mm, 40 cases), and Group C (nodule diameter ≥ 10 mm, 63 cases), with the results of surgery and pathology as the gold standard, the positive detection rate of nodules and the accuracy of diagnosis in groups A, B, and C were analyzed. Results: The positive rate of US-FNA diagnosis by ultrasound was 38.66%, which was not significantly different from the positive rate of pathological diagnosis, which was 48.74%, with no statistical significance (P > 0.05). The accuracy rate of US-FNA puncture in group B (nodule di-ameter 6~10 mm) was the highest at 95.00%, which was significantly different from that in group A (nodule diameter ≤ 5 mm), with statistical significance (P < 0.05), and was significantly different from C group (P < 0.05). There was no statistically significant difference between groups (nodule diameter ≥ 10 mm) (P > 0.05). Conclusion: Ultrasound-guided fine needle aspiration cytology diag-nosis has high clinical application value for thyroid nodules of different sizes.