肝部分切除术后肝再生的最新研究进展

Research Progress of Liver Regeneration after Partial Hepatectomy

摘要: 肝脏是人体内最主要的代谢器官，拥有强大的再生潜力。各种损伤性刺激引起肝脏损害后，再生能力增强，残肝体积及重量增加，致使肝组织结构的重建及肝功能的恢复。目前，肝脏占位病变及胆道良恶性病变在肝胆外科较为常见，肝切除术是治疗上述疾病的主要方案，术后残余肝组织不足，导致残留肝组织无法适应机体正常新陈代谢的需要，残余肝脏再生将受到影响，进而可能导致术后严重的并发症如肝功能衰竭。基于此，本文就目前关于肝切除术后肝再生过程、影响因素、评估方法等方面的研究进展作一综述。

Abstract: The liver is the most important metabolic organ in the human body and has a strong regenerative potential. After liver damage caused by various damaging stimuli, the regeneration ability is en-hanced, and the volume and weight of the residual liver increase, resulting in the reconstruction of liver tissue structure and the recovery of liver function. At present, liver space-occupying lesions and benign and malignant lesions of the biliary tract are more common in hepatobiliary surgery. Hepatectomy is the main solution for the treatment of the above diseases. The residual liver tissue after surgery is insufficient, resulting in the residual liver tissue unable to meet the needs of normal metabolism of the body, and the regeneration of the residual liver will be affected, which may lead to serious postoperative complications such as liver failure. Based on this, this article reviews the current research progress on the process of liver regeneration after hepatectomy, influencing fac-tors, and evaluation methods.