复方黄三刺外用方治疗湿热毒蕴型糖尿病足溃疡80例临床观察

The 80 Cases Treatment of Diabetic Foot Ulcer with Pattern of Dampness-Heat Toxin Amassment by Using the Compound Huangsanci External Prescription

摘要: 目的：观察复方黄三刺外用方用于医治糖尿病足溃疡的临床疗效。方法：在兰州市多家医院抉择糖尿病足溃疡患者140例，进行随机分类，随机分为空白组(标准医治)、中药组(标准医治 + 复方黄三刺外用方)。2组患者均常规使用降糖药，包含胰岛素和(或)口服降糖药，并要求按照糖尿病饮食方案严格进行饮食管制，同时进行合理运动。六周为1疗程，医治1疗程后判定疗效。结果：部分症状改善状况相比医治后中药组总有效率91.25%，显著高于空白组(P < 0.05)。血糖及糖化血红蛋白(HbA1c)与医治后2组血糖及糖化血红蛋白相比较，无显著性不同(P > 0.05)，但各组医治后与医治前相比各目标值均有所降低(P < 0.05)。疗效判定结果相比中药组有效率90% (P < 0.05)。结论：本研究表明复方黄三刺外用方治疗湿热毒蕴证糖尿病足溃疡，运用中药外用，简便易廉，疗效满意，压缩患者住院时间，节省住院经费，促进早日康复，获得良好的社会经济学效益，值得在临床和基层进一步深入钻研和推行。

Abstract: Objective: The clinical effect of Compound Huangsanci External Prescription (CHEP) for the treatment of diabetic foot ulcer was observed. Methods: 140 cases of diabetic foot ulcers patients from hospitals in Lanzhou were selected and randomly divided into the Blank groups (standard treatment), the Chinese Medicine group (standard treatment + CHEP). Two groups of patients used hypoglycemic drugs routinely, including insulin and/or oral hypoglycemic drugs, and strictly controlled diet according to the diabetic diet plan, with guided reasonable exercise. Take six weeks as 1 course and assess clinical efficacy after 1 course treatment. Results: The improvement of some symptoms compared with the traditional Chinese Medicine group after treatment, the total effective rate was 91.25%, which was significantly higher than that of the Blank group (P < 0.05). There was little difference in blood glucose and glycated hemoglobin (HbA1c) between the two groups after treatment (P > 0.05). But all indicators have decreased after treatment which compared with the pre-treatment (P < 0.05). Compared with the Chinese Medicine group, the efficacy judgment result was 90% effective (P < 0.05). Conclusion: This study shows that the treatment of diabetic foot ulcer with pattern of dampness-heat toxin amassment, by using the traditional Chinese medicine as external treatment, has the advantage of simpleness, inexpensiveness and satisfactory efficacy, which can compress patients’ hospital time, save hospitalization funds and promote early recovery. It can obtain good social and economic benefits, which is worth further study and implementation in clinical and grassroots level.