甲襞微循环检测在结缔组织病中的研究进展
Research Progress of Nailfold Microcirculation Detection in Connective Tissue Diseases
DOI: 10.12677/ACM.2022.1291246, PDF,    科研立项经费支持
作者: 孙晓莹, 柴克霞*:青海大学附属医院风湿免疫科,青海 西宁
关键词: 甲襞微循环结缔组织病雷诺现象Nailfold Microcirculation Connective Tissue Disease Raynaud Phenomenon
摘要: 微循环在生理过程中起着至关重要的作用。包括小动脉、毛细血管和小静脉,参与体温调节、血流动力学平衡维持、细胞营养供应和清除细胞代谢衍生的分解代谢产物,毛细血管袢是一种直径较小的血管,通常由单层内皮细胞构成,其分布在全身所有器官和组织。甲襞微循环检测可量化、无创、直观地显示微血管病变的情况,甲襞毛细血管异常已经被纳入ACR/EULAR制定的2013年SSc分类标准,其功能状态与结缔组织病(connective tissue disease, CTD)、外周血管等密切相关。
Abstract: Microcirculation plays a vital role in physiological processes. Arterioles, capillaries, and venules, ca-pillary loops are involved in thermoregulation, hemodynamic balance maintenance, cellular nutri-ent supply, and removal of catabolites derived from cellular metabolism. Capillary loops are small blood vessels, usually composed of a monolayer of endothelial cells, which are distributed in all or-gans and tissues throughout the body. Nailfold microcirculation detection is quantifiable, non-invasive, and intuitively displays microvascular lesions. Nailfold capillary abnormalities have been included in the 2013 SSc classification criteria formulated by ACR/EULAR. Its function and connective tissue disease (CTD connective tissue disease), peripheral vascular, etc are closely re-lated.
文章引用:孙晓莹, 柴克霞. 甲襞微循环检测在结缔组织病中的研究进展[J]. 临床医学进展, 2022, 12(9): 8628-8632. https://doi.org/10.12677/ACM.2022.1291246

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