荷叶生物碱的研究进展
Research Progress of Alkaloids from Lotus Leaves
DOI: 10.12677/ACM.2022.1291258, PDF,   
作者: 曹 天*, 卫雅琪, 曹沐筝, 李 枫：青海大学研究生院，青海 西宁；闫 军#：北京清华长庚医院肝胆胰中心，北京；康 君：天津大学生命科学学院，天津；张 冬：蚌埠医学院研究生院，安徽 蚌埠
关键词: 荷叶碱；药理作用；作用机制；Nuciferine； Pharmacological Activity； Mechanism
摘要: 荷叶碱是一种从睡莲科植物莲(Nelumbo nucifera Gaertn)中提取的一种阿朴啡类生物碱，近年的药理研究表明，其具有降脂、降糖、抗炎抑菌、抗动脉粥样硬化、抗病毒、抗肿瘤等多种药理作用。且毒性低，不良反应少，拥有广阔的开发前景，是近年来药物研究的热点之一。现综述荷叶生物碱药理研究进展，希望为其临床应用及进一步研究提供新思路。
Abstract: Lotus leaf alkaloid is an aporphine alkaloid extracted from lotus in the family of Nymphaeaceae. Recent pharmacological studies have shown that it has many pharmacological effects, such as li-pid-lowering, hypoglycemic, anti-inflammatory and bacteriostatic, anti atherosclerosis, anti-virus, anti-tumor and so on. With low toxicity and less adverse reactions, it has broad development pro-spects and is one of the hotspots of drug research in recent years. This paper reviews the pharma-cological research progress of lotus leaf alkaloids, hoping to provide new ideas for its clinical appli-cation and further research.
文章引用：曹天, 闫军, 康君, 卫雅琪, 张冬, 曹沐筝, 李枫. 荷叶生物碱的研究进展[J]. 临床医学进展, 2022, 12(9): 8720-8725. https://doi.org/10.12677/ACM.2022.1291258

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