高压氧治疗对急性心肌梗死的研究进展

Advances in Hyperbaric Oxygen Therapy for Acute Myocardial Infarction

摘要: 在心肌发生梗死后，心肌梗死面积的大小和心功能的改变对病人的预后具有着重要意义，并直接影响着死亡率。通过及时合理地限制心肌梗死面积发展，可以有效改善心功能不全，改善预后及生活质量，进而减少该病的死亡率。有科学研究已经证实，如果病人在一个大气压以上吸氧时，可以提高血内氧的物理溶解率，使组织细胞内的氧气含量进而增多，有利于缺血、损伤的心肌细胞得到一定程度的恢复，又可延缓和阻止急性心肌梗死面积的进展，保护损伤的心肌，进而使心脏功能得到一定的改善。目前临床应用高压氧治疗心肌梗死尚无明确指南，本文就高压氧治疗对急性心肌梗死的研究进展进行综述。

Abstract: After myocardial infarction, the size of the infarct and changes in cardiac function are of great im-portance to the patient’s prognosis and have a direct impact on mortality. By limiting the size of myocardial infarction in a timely and appropriate manner, cardiac insufficiency can be improved and the prognosis and quality of life can be improved, thereby reducing the mortality of the disease. Scientific research has confirmed that if a patient is receiving oxygen at a pressure above one at-mosphere, the physical dissolution rate of oxygen in the blood can be increased, resulting in an in-crease in the oxygen content of the tissue cells, which is conducive to a certain degree of recovery of the ischaemic and damaged myocardial cells, and can also delay and stop the progression of the acute myocardial infarction, protecting the damaged myocardium and thus improving the function of the heart. There are no clear guidelines for the clinical application of hyperbaric oxygen for the treatment of myocardial infarction. This article reviews the progress of research on hyperbaric ox-ygen therapy for acute myocardial infarction.