孕妇阴道微生态菌群与维生素D水平相关性的研究进展
Research Progress on the Correlation between Vaginal Microbiota and Vitamin D Level in Pregnant Women
DOI: 10.12677/ACM.2022.12101313, PDF,   
作者: 侯晨阳：西安医学院，陕西 西安；张利侠*：陕西省人民医院检验科，陕西 西安
关键词: 25-羟维生素D；孕妇；细菌性阴道病；阴道菌群；25-Hydroxyvitamin D； Pregnant Women； Bacterial Vaginosis； Vaginal Microbiota
摘要: 妊娠期细菌性阴道病(bacterial vaginosis, BV)是由于孕妇妊娠期生理状态及阴道内微环境改变从而导致的阴道正常菌群失调。妊娠期妇女阴道微生态菌群失调将可能进一步引起宫内、胎儿感染以及各种不良妊娠结局。近年来有研究表明维生素D会影响生殖系统炎症及免疫调节的许多方面；这些发现引导出维生素D缺乏可能与妊娠期BV存在关联，并且提出不同维生素D状态可能改变阴道菌群这样的假设。如果能发现维生素D与阴道微生态菌群间存在联系，便有可能通过补充维生素D改善BV孕妇症状。现就维生素D与阴道微生态菌群的相关性研究进展进行综述。
Abstract: Bacterial vaginosis (BV) during pregnancy is a disorder of normal vaginal flora caused by changes in the physiological state of pregnant women and vaginal microenvironment. The imbalance of vaginal microflora in pregnant women will further lead to intrauterine and fetal infections and various ad-verse pregnancy outcomes. In recent years, studies have shown that vitamin D can affect many as-pects of inflammation and immune regulation of the reproductive system. These findings lead to the hypothesis that vitamin D deficiency may be associated with BV during pregnancy and that differ-ent vitamin D status may alter the vaginal flora. If the relationship between vitamin D and vaginal microflora can be found, it is possible to improve the symptoms of BV pregnant women by vitamin D supplementation. This article reviews the research progress of the correlation between vitamin D and vaginal microbiota.
文章引用：侯晨阳, 张利侠. 孕妇阴道微生态菌群与维生素D水平相关性的研究进展[J]. 临床医学进展, 2022, 12(10): 9081-9085. https://doi.org/10.12677/ACM.2022.12101313

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