角膜屈光术后干眼的发病情况和影响因素的研究进展

Research Progress on the Prevalence and Influencing Factors of Dry Eye after Corneal Refractive Surgery

摘要: 随着医疗技术的不断完善与发展，角膜屈光手术作为一种具有较高安全性和有效性的矫正常规屈光不正的术式，已在临床上广泛应用。自从角膜屈光手术问世以来，其手术方式也在不断更新，该手术可根据是否采用激光分为激光性和非激光性手术，由于非激光性手术其预测性、准确性较差，现已极少用于常规屈光不正的精准矫正。目前临床上常见激光性角膜屈光手术主要有飞秒激光辅助下准分子激光原位角膜磨镶术(femtosecond laser-assisted laser in situ keratomileusis, FS-LASIK)、飞秒激光小切口角膜基质透镜取出术(small incision lenticule extraction, SMILE)、经上皮准分子激光角膜切削术(Trans-epithe- lium Photorefractive Keratectomy, T-PRK)等，干眼是角膜屈光术后患者最常见的主诉之一，易影响术后效果及满意度，因此受到了眼科医师的广泛关注。本文针对角膜屈光术后干眼症发病影响因素以及相关情况的研究进展进行分析，仅供参考。

Abstract: With the continuous improvement and development of medical technology, keratomileusis has been widely used in clinical practice as a highly safe and effective procedure to correct conventional refractive errors. Since the introduction of keratomileusis, the surgical approach has been con-stantly updated. The procedure can be divided into laser and non-laser surgery depending on whether a laser is used, and non-laser surgery is rarely used for the precise correction of conven-tional refractive error due to its poor predictability and accuracy. At present, the main common la-ser keratomileusis procedures include femtosecond laser-assisted laser in situ keratomileusis (femtosecond laser-assisted laser in situ keratomileusis, FS-LASIK), small incision lenticule extrac-tion (small incision lenticule extraction, SMILE), Trans-epithelium Photorefractive Keratectomy (Trans-epithelium Photorefractive Keratectomy, T-PRK), etc. Dry eye is one of the most common complaints of post-keratomileusis patients and is of wide concern to ophthalmologists as it tends to affect postoperative outcomes and satisfaction. This article analyzes the factors influencing the de-velopment of dry eye after keratomileusis and the progress of research on the situation, for refer-ence only.