母乳嗅觉刺激对新生儿操作性疼痛及喂养效果的Meta分析
Effect of Olfactory Stimulation of Breast Milk on Neonatal Operational Pain and Feeding: A Meta-Analysis
DOI: 10.12677/ACM.2022.12101360, PDF,   
作者: 侯凤霞, 邢梦莹, 胡宏美, 陈思婕：延安大学医学院，陕西 延安；西安交通大学第一附属医院，陕西 西安；申良荣*：西安交通大学第一附属医院，陕西 西安；王红兵：定西市中医院，甘肃 定西
关键词: 母乳；嗅觉刺激；新生儿；操作性疼痛；喂养；Meta分析；Breast Milk； Olfactory Stimulation； Neonate； Operational Pain； Feeding； Meta-Analysis
摘要: 目的：评价母乳嗅觉刺激对新生儿操作性疼痛及喂养效果。方法：系统检索从建库至2021年11月期间PubMed、Embase、Web of Science、Cochrane Library、中国生物医学文献数据库、中国知网、维普和万方数据库中有关母乳嗅觉刺激在新生儿护理中应用效果的随机对照试验。采用RevMan 5.3统计软件进行Meta分析。结果：纳入10项研究，共624例新生儿。结果显示，母乳嗅觉刺激能降低新生儿操作性疼痛评分(P < 0.05)，缩短达经口喂养过渡时间(P < 0.05)；但对新生儿致痛性操作期间的哭闹持续时间和出院时体重无明显效果(P > 0.05)。根据母乳干预的量进行亚组分析，结果显示2 ml母乳可提高新生儿致痛性操作期间的血氧饱和度(P < 0.05)，5 ml母乳未显示出明显的优势(P > 0.05)。结论：母乳嗅觉刺激可缓解新生儿操作性疼痛，促进新生儿喂养进程。
Abstract: Objective: To evaluate the effect of breast milk olfactory stimulation on neonatal operational pain and feeding. Methods: PubMed, Embase, Web of Science, Cochrane Library, CBM, CNKI, VIP and Wanfang database were retrieved for relevant randomized controlled trials of the effect of breast milk olfactory stimulation in neonatal care from the establishment of databasesto November 2021. Meta-analysis was conducted by RevMan 5.3. Results: Totally 10 RCTs involving 624 neonates. The results suggested that breast milk olfactory stimulation could reduce the score of procedural pain of neonates (P < 0.05) and shorten the transition time to oral feeding (P < 0.05); But there was no sig-nificant effect for crying time during painful operation and weight at discharge (P > 0.05). Subgroup analysis was conducted according to amount of breast milk intervention. The results showed that 2 ml of breast milk could improve the blood oxygen saturation during painful operation (P < 0.05), while 5 ml of breast milk did not significant advantage (P > 0.05). Conclusions: Breast milk olfactory stimulation can alleviate procedural pain and promote the process of neonatal feeding.
文章引用：侯凤霞, 邢梦莹, 申良荣, 胡宏美, 陈思婕, 王红兵. 母乳嗅觉刺激对新生儿操作性疼痛及喂养效果的Meta分析[J]. 临床医学进展, 2022, 12(10): 9403-9411. https://doi.org/10.12677/ACM.2022.12101360

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