脑梗死周围区FVH数量与CT灌注状态相关性研究
Study on the Correlation between the Number of FVH and CT Perfusion State in the Surrounding Area of Cerebral Infarction
摘要: 目的：探讨脑梗死患者梗死周围区MRI液体衰减反转恢复序列血管高信号(Fluid-attenuated inver-sion recovery Vascular Hyperintensity, FVH)数量与CT灌注成像(Computerized Tomography Perfu-sion, CTP)各参数之间的相关性。方法：回顾性分析75例行头部MRI及头部CTP检查的急性脑梗死患者，根据有无FVH征象分为有FVH组(n = 54)和无FVH组(n = 21)，分析两组的临床基本资料、CTP参数有无差异性，并分析有FVH组的FVH数量与CTP参数之间的相关性。结果：有FVH组和无FVH组间rMTT、rTTP、rCBV差异性明显，而rCBF差异性较差(P = 0.650)；有FVH组FVH数量与rTTP、rMTT、rCBV间相关性密切，而与rCBF无明显相关性。结论：FVH征的出现代表梗死周围区侧支循环的建立，在有FVH征出现的情况下，梗死周围区的灌注情况得到了明显的改善；FVH数量越多，梗死周围区的血液灌注量越大，对于缓解梗死周围区脑组织的缺血越有利，从而更有利于患者的预后。
Abstract: Objective: To investigate the correlation between the number of fluid attenuated inversion recovery vascular hyperintensity (FVH) and the parameters of CT perfusion imaging (CTP) in patients with cerebral infarction. Methods: Retrospective analysis of 75 patients with acute cerebral infarction examined by head MRI and head CTP, according to the signs of FVH, the patients were divided into two groups: group with FVH (n = 54) and group without FVH (n = 21), analyze whether there is dif-ference in clinical basic data and CTP parameters between the two groups, and analyzed the corre-lation between the number of FVH and CTP data. Results: There were significant differences in rMTT, rTTP and rCBV between FVH group and non FVH group, but there was no significant difference in rCBF (P = 0.650); In FVH group, the number of FVH was closely correlated with rTTP, rMTT and rCBV, but not with rCBF. Conclusions: The appearance of FVH sign represents the establishment of collat-eral circulation in the periinfarct area. In the case of FVH sign, the perfusion around the infarct was significantly improved. The more the number of FVH, the greater the blood perfusion in the pe-riinfarct area, which is more beneficial to relieve the ischemia of the periinfarct brain tissue, and thus more conducive to the prognosis of patients.
文章引用：王银成, 刘学军. 脑梗死周围区FVH数量与CT灌注状态相关性研究[J]. 临床医学进展, 2022, 12(10): 9417-9424. https://doi.org/10.12677/ACM.2022.12101362

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