常见实验室指标与肺栓塞患者预后的研究进展

Research Progress of Common Laboratory Indicators and Prognosis of Patients with Pulmonary Embolism

摘要: 肺栓塞(pulmonary embolism, PE)是一种严重的疾病，具有重大的全球性影响。其临床表现缺乏特异性，预后差异极大，因此为首次诊断的科室急诊科带来了巨大的挑战。对PE患者的预后评估是推动其治疗的关键，寻找新的预后因素是更准确地估计短期不良事件的核心问题。本文描述了急诊科常见实验室指标，如血钙、中性粒细胞/淋巴细胞比值、血小板/淋巴细胞比值、D-二聚体等对PE患者预后的影响，从而指导PE患者个体化治疗、提高PE患者生存率。

Abstract: Pulmonary embolism (PE) is a serious disease with significant global impact. Its clinical presenta-tion lacks specificity and prognosis is highly variable, thus posing a huge challenge to the emergen-cy department for first-time diagnosis. Prognostic assessment of PE patients is the key to promoting their treatment, and finding new prognostic factors is the core issue for more accurate estimation of short-term adverse events. This article describes the impact of common laboratory indicators in the emergency department on the prognosis of PE patients, such as serum calcium, neutrophil to lym-phocyte ratio, platelet to lymphocyte ratio, D-dimer and so on, to guide individualized treatment of PE patients, improve survival rate of PE patients.