基于古今医案平台的中医药治疗鼻后滴漏综合征的用药规律研究

Study on the Medication Law of Traditional Chinese Medicine in the Treatment of Postnasal Drip Syndrome Based on the Ancient and Modern Medical Record Platform

摘要: 目的：基于古今医案平台研究现代中医药治疗鼻后滴漏的用药规律，为临床治疗鼻后滴漏提供用药参考。方法：通过检索CNKI、万方、维普等数据库收集鼻后滴漏综合征现代文献的有效验案，经过数据筛选、清洗、标准化处理，并建立标准化医案数据库，利用古今医案平台频次统计、关联分析、聚类分析、复杂网络分析等数据分析方法，分析中医药治疗鼻后滴漏综合征的用药频次、四气、五味、归经、常用药对、核心处方等用药规律，并进行可视化展示。结果：本研究共纳入处方55首，涉及药物174味，其中使用频次较高的药物为麻黄、杏仁、桔梗、甘草、辛夷、苍耳子、蝉蜕等；药物四气多以温为主、寒及平次之；五味以辛、苦、甘味为主；药物归经多入肺、肝、胃经；使用频次较高的药物组合包括“甘草–桔梗”“甘草–杏仁”“桔梗–杏仁”等。结论：现代中医治疗PNDS以疏风清热，化痰利咽为主要治法，标本同治。

Abstract: Objective: To study the medication rules of modern Chinese medicine in the treatment of postnasal drip based on the ancient and modern medical record platform, and to provide medication reference for clinical treatment of postnasal drip. Methods: By searching CNKI, Wanfang, VIP and other databases, the effective cases of modern literature on postnasal drip syndrome were collected. After data screening, cleaning and standardization, a standardized medical record database was established. Frequency statistics and correlation analysis of ancient and modern medical record platforms were used. Data analysis methods such as cluster analysis, complex network analysis, etc., were used to analyze the medication frequency, four qi, five flavors, meridians, commonly used drug pairs, and core prescriptions of traditional Chinese medicine in the treatment of postnasal drip syndrome, and visualize them. Results: A total of 55 prescriptions were included in this study, involving 174 drugs. Among them, the most frequently used drugs were ephedra, almond, platycodon, licorice, Xinyi, Xanthium, and cicada. The four qi of the drug are mainly warm, cold and calm; the five flavors are mainly acrid, bitter and sweet; the medicines enter the lung, liver, and stomach meridians; the drug combinations with higher frequency include “licorice-platycodon”, “licorice-almond”, “platycodon-almond” and so on. Conclusion: Modern Chinese medicine treats PNDS with the main methods of clearing away heat, dissolving phlegm and sore throat, and treating both the symptoms and root causes.