腹腔镜袖状胃切除术对青少年肥胖患者的短期疗效与安全性分析

Short-Term Efficacy and Safety of Laparoscopic Sleeve Gastrectomy in Obese Adolescent Patients

摘要: 目的：分析腹腔镜袖状胃切除术(laparoscopic sleeve gastrectomy, LSG)对青少年肥胖患者的短期疗效与安全性。方法：回顾性分析2020年1月至2022年1月在安徽医科大学第二附属医院普外科行LSG的青少年肥胖患者53例，收集手术时间、术中出血量、术后住院时间、术后并发症及术后3个月的体重变化和相关代谢指标情况进行比较。结果：53例青少年肥胖患者手术过程顺利，术后未出现严重并发症。术后3个月体重、BMI明显下降，差异有统计学意义(P < 0.05)，EWL%为(52.98% ± 15.27%)。术后3个月糖代谢指标(空腹血糖、空腹胰岛素、空腹C肽、糖化血红蛋白)、脂代谢指标(血清总胆固醇、甘油三酯、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇)及尿酸等代谢指标均较术前明显改善，差异有统计学意义(P < 0.05)。结论：腹腔镜袖状胃切除术治疗青少年肥胖安全可行，术后短期内体重下降明显，相关合并症可得到临床缓解或治愈。

Abstract: Objective: To analyze the short-term efficacy and safety of laparoscopic sleeve gastrectomy (LSG) in obese adolescent patients. Methods: A retrospective analysis of 53 obese adolescent patients who underwent LSG in the General Surgery Department of the Second Hospital of Anhui Medical Univer-sity from January 2020 to January 2022. The operation time, intraoperative blood loss, postopera-tive hospital stay, postoperative complications, body weight changes and related metabolic indica-tors at 3 months after surgery were compared. Results: The operation of the 53 adolescent obese patients went smoothly without serious postoperative complications. The body weight and BMI de-creased significantly 3 months after operation, and the difference was statistically significant (P < 0.05), and the EWL% was (52.98% ± 15.27%). Glucose metabolism indexes (fasting blood glucose, fasting insulin, fasting C-peptide, glycosylated hemoglobin), lipid metabolism indexes (serum total cholesterol, triglyceride, low-density lipoprotein cholesterol, high- density lipoprotein cholesterol) and uric acid were significantly improved compared with those before operation, and the difference was statistically significant (P < 0.05). Conclusions: Laparoscopic sleeve gastrectomy is safe for the treatment of obesity in adolescents with significant weight loss in the short term after surgery, and related complications can be clinically relieved or cured.