自发性脑出血后血肿再扩大的常见CT征象研究进展
Research Progress on Common CT Signs of Hematoma Expansion after Spontaneous In-tracerebral Hemorrhage
摘要: 脑出血发病率虽然只占脑卒中的20%,其致残率和死亡率却位居卒中疾病首位。出血后再扩大是临床不良预后及神经功能恶化的独立危险因素。因头颅CT作为脑出血金标准,从影像学上预测脑出血再扩大研究很多,本文对于自发性脑出血再扩大常见影像学征象进行再归纳。
Abstract: Although the incidence of intracerebral hemorrhage only accounts for 20% of stroke, its disability rate and mortality are the first stroke diseases. Hematoma expansion is an independent risk factor for poor clinical prognosis and neurological deterioration. As head CT is the gold standard of intrac-erebral hemorrhage, there are many studies on the imaging prediction of intracerebral hematoma expansion. In this paper, the common imaging signs of spontaneous intracerebral hemorrhage reenlargement were summarized.
文章引用:戴佳霖, 刘丹, 刘羽遥, 文瑶, 喻媛, 杨全. 自发性脑出血后血肿再扩大的常见CT征象研究进展[J]. 临床医学进展, 2022, 12(11): 10304-10311. https://doi.org/10.12677/ACM.2022.12111486

参考文献

[1] Hostettler, I.C., Seiffge, D.J. and Werring, D.J. (2019) Intracerebral Hemorrhage: An Update on Diagnosis and Treat-ment. Expert Review of Neurotherapeutics, 19, 679-694. [Google Scholar] [CrossRef] [PubMed]
[2] Dowlatshahi, D., Demchuk, A.M., Flaherty, M.L., et al. (2011) Defining Hematoma Expansion in Intracerebral Hemorrhage: Relationship with Patient Outcomes. Neurology, 76, 1238-1244. [Google Scholar] [CrossRef
[3] Maas, M.B. (2020) Intensive Blood Pressure Reduction in Patients with Intracerebral Hemorrhage and Extreme Initial Hypertension: Primum Non Nocere. JAMA Neurology, 77, 1351-1352. [Google Scholar] [CrossRef] [PubMed]
[4] Li, Q., Warren, A.D., Qureshi, A.I., et al. (2020) Ultra-Early Blood Pressure Reduction Attenuates Hematoma Growth and Improves Outcome in Intracerebral Hemor-rhage. Annals of Neurology, 88, 388-395. [Google Scholar] [CrossRef] [PubMed]
[5] Wada, R., Aviv, R.I., Fox, A.J., et al. (2007) CT Angiography “Spot Sign” Predicts Hematoma Expansion in Acute Intracerebral Hemorrhage. Stroke, 38, 1257-1262. [Google Scholar] [CrossRef
[6] Demchuk, A.M., Dowlatshahi, D., Rodriguez-Luna, D., et al. (2012) Prediction of Haematoma Growth and Outcome in Patients with Intracerebral Haemorrhage Using the CT-Angiography Spot Sign (PREDICT): A Prospective Observational Study. The Lancet Neurology, 11, 307-314. [Google Scholar] [CrossRef
[7] Fu, F., Sun, S., Liu, L., et al. (2018) Iodine Sign as a Novel Predictor of Hematoma Expansion and Poor Outcomes in Primary Intracerebral Hemorrhage Patients. Stroke, 49, 2074-2080. [Google Scholar] [CrossRef
[8] Orito, K., Hirohata, M., Nakamura, Y., et al. (2016) Leakage Sign for Primary Intracerebral Hemorrhage: A Novel Predictor of Hematoma Growth. Stroke, 47, 958-963. [Google Scholar] [CrossRef
[9] Sun, S.J., Gao, P.Y., Sui, B.B., et al. (2013) “Dynamic Spot Sign” on CT Perfusion Source Images Predicts Haematoma Expansion in Acute Intracerebral Haemor-rhage. European Radiology, 23, 1846-1854. [Google Scholar] [CrossRef] [PubMed]
[10] Dowlatshahi, D., Smith, E.E., Flaherty, M.L., et al. (2011) Small Intracerebral Haemorrhages Are Associated with Less Haematoma Expansion and Better Outcomes. International Jour-nal of Stroke, 6, 201-206. [Google Scholar] [CrossRef] [PubMed]
[11] 王文娟, 陆菁菁, 陈胜云, 等. 原发性脑出血超急性期血肿增长速度与临床预后的关系研究[J]. 中国卒中杂志, 2018, 13(5): 437-43.
[12] Xiang, Y., Zhang, T., Li, Y., et al. (2020) Comparison of Ultra-Early Hematoma Growth and Common Noncontrast Computed Tomography Features in Predicting Hematoma Enlargement in Patients with Spontaneous Intracerebral Hemorrhage. World Neurosurgery, 134, e75-e81. [Google Scholar] [CrossRef] [PubMed]
[13] Wang, W.J., Lu, J.J., Liu, L.P., et al. (2021) Ultraearly Hematoma Growth in Acute Spontaneous Intracerebral Hemorrhage Predicts Early and Long-Term Poor Clinical Out-comes: A Prospective, Observational Cohort Study. Frontiers in Neurology, 12, Article ID: 747551. [Google Scholar] [CrossRef] [PubMed]
[14] Barras, C.D., Tress, B.M., Christensen, S., et al. (2009) Density and Shape as CT Predictors of Intracerebral Hemorrhage Growth. Stroke, 40, 1325-1331. [Google Scholar] [CrossRef
[15] Li, Q., Zhang, G., Huang, Y.J., et al. (2015) Blend Sign on Computed Tomography: Novel and Reliable Predictor for Early Hematoma Growth in Patients with Intracerebral Hemorrhage. Stroke, 46, 2119-2123. [Google Scholar] [CrossRef
[16] Li, Y., Ren, S., Wang, L., et al. (2021) Is the CT Blend Sign Composed of Two Parts of Blood with Different Age? Neurocritical Care, 35, 367-378. [Google Scholar] [CrossRef] [PubMed]
[17] 李颖慧. 脑出血头颅CT混合征形成机制与血液组分关系的系统研究[D]: [博士学位论文]. 贵阳: 贵州医科大学, 2021.
[18] Selariu, E., Zia, E., Brizzi, M., et al. (2012) Swirl Sign in Intracerebral Haemorrhage: Definition, Prevalence, Reliability and Prognostic Value. BMC Neurology, 12, Article No. 109. [Google Scholar] [CrossRef] [PubMed]
[19] Li, Q., Zhang, G., Xiong, X., et al. (2016) Black Hole Sign: Novel Imaging Marker That Predicts Hematoma Growth in Patients with Intracerebral Hemorrhage. Stroke, 47, 1777-1781. [Google Scholar] [CrossRef
[20] 陈凯, 李涛, 吴涛, 等. 黑洞征、混合征及斑点征对早期脑血肿扩张预测价值的对比研究[J]. 湘南学院学报(医学版), 2019, 21(1): 8-12.
[21] Chen, Y., Tian, L., Wang, L., et al. (2020) Black Hole Sign on Noncontrast Computed Tomography in Predicting Hematoma Expansion in Patients with Intracerebral Hemorrhage: A Meta-Analysis. Current Medical Imaging, 16, 878-886. [Google Scholar] [CrossRef] [PubMed]
[22] Schlunk, F. and Greenberg, S.M. (2015) The Patho-physiology of Intracerebral Hemorrhage Formation and Expansion. Translational Stroke Research, 6, 257-263. [Google Scholar] [CrossRef] [PubMed]
[23] Morotti, A., Busto, G., Scola, E., et al. (2021) Association be-tween Perihematomal Perfusion and Intracerebral Hemorrhage Shape. Neuroradiology, 63, 1563-1567. [Google Scholar] [CrossRef] [PubMed]
[24] Li, Q., Liu, Q.J., Yang, W.S., et al. (2017) Island Sign: An Im-aging Predictor for Early Hematoma Expansion and Poor Outcome in Patients with Intracerebral Hemorrhage. Stroke, 48, 3019-3025. [Google Scholar] [CrossRef
[25] Shimoda, Y., Ohtomo, S., Arai, H., et al. (2017) Satellite Sign: A Poor Outcome Predictor in Intracerebral Hemorrhage. Cerebrovascular Diseases, 44, 105-112. [Google Scholar] [CrossRef] [PubMed]
[26] Deng, L., Zhang, G., Wei, X., et al. (2019) Comparison of Satellite Sign and Island Sign in Predicting Hematoma Growth and Poor Outcome in Patients with Primary Intracerebral Hemorrhage. World Neurosurgery, 127, e818-e825. [Google Scholar] [CrossRef] [PubMed]
[27] 范丽, 黄劲柏. CT灌注成像对自发性脑出血的研究进展[J]. 临床放射学杂志, 2020, 39(4): 819-821.
[28] 白小飞, 寇欣, 樊宇耕, 等. CT灌注成像对高血压性脑出血患者亚急性期血肿量的评估价值[J]. 中华实用诊断与治疗杂志, 2019, 33(2): 172-174.
[29] 王晓晨, 王思慧, 赵雪宁, 等. 急性脑出血“动态点征”区域CT灌注参数定量评估血肿扩大[J]. 中国医学影像技术, 2022, 38(8): 1134-1138.
[30] 陈媛媛, 周治明, 王世科, 等. 临床-影像组学联合模型预测自发性脑出血后早期血肿扩大的研究[J]. 中华神经医学杂志, 2021, 20(11): 1117-1123.