四川凉山地区儿童过敏性紫癜肾损害的危险因素分析

Children in Liangshan Area of Sichuan Prov-ince with Henoch-Sch?nlein Purpura Kidney Damage Risk Factor Analysis

摘要: 目的：探讨四川凉山地区儿童过敏性紫癜(HSP)发生肾脏损害的危险因素。方法：对174例凉山地区过敏性紫癜患儿的临床资料进行分析。结果：174例过敏性紫癜患儿中男女之间的比例为1.15:1；彝汉之间的比例为2.05:1；发病年龄集中在2~8岁(占52.3%)；发病地区集中在农村(占76.4%)；发病季节主要集中在春夏季节(占66.1%)；首发症状以皮肤型为主(占35.6%)；年龄 > 8岁、首发症状为皮肤紫癜 + 腹痛以及皮肤紫癜 + 腹痛 + 关节痛的人群是过敏性紫癜出现肾脏损害的独立危险因素。结论：四川凉山地区儿童过敏性紫癜农村患儿发病较多，多集中在春夏季节发病，首发症状以皮肤型为主。年龄 > 8岁、首发症状为皮肤紫癜 + 腹痛以及皮肤紫癜 + 腹痛 + 关节痛的人群与肾脏损害的发生密切相关。

Abstract: Objective: To investigate the risk factors for renal damage of Henoch-Schönlein purpura (HSP) in children in Liangshan area of Sichuan Province. Methods: The clinical data of 174 children with Henoch-Schönlein purpura in Liangshan were analyzed. Results: The ratio of men and women in 174 children with Henoch-Schönlein was 1.15:1, and the ratio between Yi and Han was 2.05:1, and the age of onset was concentrated in 2 - 8 years old (52.3%). The incidence areas are concentrated in rural areas (76.4%); The incidence season is mainly concentrated in spring and summer (66.1%); The first symptoms were mainly cutaneous (35.6%); People aged >8 years with first symptoms of purpura + abdominal pain and skin purpura + abdominal pain + arthralgia are independent risk factors for renal damage in Henoch-Schönlein purpura. Conclusions: Children with henoch-schönlein purpura in Liangshan area of Sichuan Province have more incidence, mostly concentrated in spring and summer, and the first symptoms are mainly skin-type. People aged >8 years with the first symptoms of purpura + abdominal pain and skin purpura + abdominal pain + arthralgia are closely related to the occurrence of renal damage.