根除幽门螺旋杆菌前后患者GerdQ评分变化情况分析

Analysis of Changes of GerdQ Score before and after Eradication of H. pylori

摘要: 目的：本研究旨在探究根除幽门螺旋杆菌(Hp)前后患者GerdQ评分变化情况，并探讨影响评分改变的危险因素。方法：本研究纳入162例于青岛大学附属医院成功根除Hp的患者，在其治疗前及治疗1月以上复查时分别检测其GerdQ评分。同时，通过门诊及随访收集患者既往史及个人史，分析性别、年龄、既往病史等对于GerdQ评分变化的影响情况。结果：患者成功根除Hp后其GerdQ评分较前明显升高(p = 0.005)，且女性(p = 0.031)与既往胃食管反流病(Gerd)病史(p = 0.011)是根除Hp后GerdQ评分升高的独立危险因素，两者与评分升高呈正相关。结论：根除Hp会导致GerdQ评分升高，女性及既往Gerd病史是其独立危险因素。

Abstract: Objective: The aim of this study was to investigate the changes in GerdQ scores of patients before and after eradication of Helicobacter pylori (Hp) and to investigate the risk factors affecting the changes in scores. Methods: This study included 162 patients who were successfully eradicated Hp from the Affiliated Hospital of Qingdao University, and their GerdQ scores were measured before treatment and at the follow-up examination more than 1 month after treatment. At the same time, the past and personal histories of the patients were collected. The influence of gender, age and past medical history on the change of GerdQ score was analyzed. Results: GerdQ scores were significantly higher after successful Hp eradication (p = 0.005), and female (p = 0.031) and previous history of gastroesophageal reflux disease (GERD) (p = 0.011) were independent risk factors for higher GerdQ scores after Hp eradication, and both were positively associated with higher scores. Conclusion: Hp eradication leads to the elevation of GerdQ scores, while women and previous history of Gerd are independent risk factors for this.