有机小分子与血清白蛋白相互作用研究进展

Research Progress on the Interaction between Small Organic Molecules and Serum Albumin

摘要: 在有机小分子与血清白蛋白相互作用领域，近年来受到重视并逐步开展深入的研究，通常采用荧光光谱法作为主要分析方法、并辅之以紫外吸收光谱法、拉曼光谱法、圆二色光谱法、分子对接技术、等温滴定热量法等方法，本文对近年来采用上述方法进行的研究进行了综合评述。在查阅近年文献后，介绍了有机小分子与血清白蛋白相互作用的进展，总结了本方向的相关研究方法，并对该领域未来的发展方向进行了分析、预测和展望。

Abstract: In the field of interaction between small organic molecules and serum albumin, attention has been paid and in-depth research has been conducted in recent years. Fluorescence spectroscopy is usually used as the main analytical method, supplemented by ultraviolet absorption spectroscopy, Raman spectroscopy, circular dichroism spectroscopy, molecular docking technology, isothermal titration heat method and other methods. This paper gives a comprehensive review of recent studies using the above methods. After reviewing the recent literature, this paper introduces the progress of the interaction between small organic molecules and serum albumin, summarizes the relevant research methods in this direction, and analyzes, predicts and looks forward to the future development direction of this field.