甲状旁腺识别技术最新研究及其进展
The Latest Research and Progress of Parathyroid Identification Technology
摘要: 甲状旁腺是钙调节的关键腺体。在甲状腺手术当中保存甲状旁腺对于避免术后甲状旁腺功能减退至关重要。目前尚无术中甲状旁腺识别的指南,目前的方法主要依赖于手术医生的经验。一种准确、快速识别甲状旁腺的技术将是一种有用的术中辅助手段。这篇综述旨在评估亚甲蓝(methylene blue, MB)、吲哚菁绿(indocyanine green, ICG)血管造影、近红外自身荧光(near-infrared autofluorescence, NIRAF)这几种方式并检查其在术中甲状旁腺识别中的实用性。
Abstract: The parathyroid gland is a key gland for calcium regulation. Preservation of the parathyroid gland during thyroid surgery is essential to avoid postoperative hypothyroidism. Currently, there are no guidelines for intraoperative identification of the parathyroid gland, and current methods mainly depend on the experience of the surgeon. This review aims to evaluate the near-infrared autofluorescence (near-infrared) of methylene blue (MB) indocyanine green (ICG) angiography autofluorescence (NIRAF) and examine its practicality for intraoperative parathyroid identification.
文章引用:胡光. 甲状旁腺识别技术最新研究及其进展[J]. 临床医学进展, 2022, 12(12): 11338-11342. https://doi.org/10.12677/ACM.2022.12121634

参考文献

[1] Ritter, K., Elfenbein, D., Schneider, D.F., et al. (2015) Hypoparathyroidism after Total Thyroidectomy: Incidence and Resolution. Journal of Surgical Research, 197, 348-353. [Google Scholar] [CrossRef] [PubMed]
[2] Ready, A.R. and Barnes, A.D. (1994) Complications of Thyroidectomy. British Journal of Surgery, 81, 1555-1556. [Google Scholar] [CrossRef] [PubMed]
[3] Almquist, M., Ivarsson, K., Nordenström, E. and Bergenfelz, A. (2018) Mortality in Patients with Permanent Hypoparathyroidism after Total Thyroidectomy. British Journal of Surgery, 105, 1313-1318. [Google Scholar] [CrossRef] [PubMed]
[4] Kakava, K., Tournis, S., Papadakis, G., et al. (2016) Postsurgical Hypoparathyroidism: A Systematic Review. In Vivo, 30, 171-179.
[5] Brandi, M.L., Bilezikian, J.P., Shoback, D., et al. (2016) Management of Hypoparathyroidism: Summary Statement and Guidelines. The Journal of Clinical Endocrinology & Metabolism, 101, 2273-2283. [Google Scholar] [CrossRef] [PubMed]
[6] Tang, J.A., Salapatas, A.M., Bonzelaar, L.B. and Friedman, M. (2018) Parathyroidectomy for the Treatment of Hyperparathyroidism: Thirty-Day Morbidity and Mortality. Laryngoscope, 128, 528-533. [Google Scholar] [CrossRef] [PubMed]
[7] Schirmer, R.H., Adler, H., Pickhardt, M. and Mandelkow, E. (2011) Lest We Forget You—Methylene Blue.... Neurobiology of Aging, 32, 2325.e7-2325.e 16. [Google Scholar] [CrossRef] [PubMed]
[8] Pollack, G., Pollack, A., Delfiner, J. and Fernandez, J. (2009) Parathyroid Surgery and Methylene Blue: A Review with Guidelines for Safe Intraoperative Use. Laryngoscope, 119, 1941-1946. [Google Scholar] [CrossRef] [PubMed]
[9] Moriyama, T., Kageyama, K., Nigawara, T., et al. (2007) Diagnosis of a Case of Ectopic Parathyroid Adenoma on the Early Image of 99mTc-MIBI Scintigram. Endocrine Journal, 54, 437-440. [Google Scholar] [CrossRef
[10] van der Vorst, J.R., Schaafsma, B.E., Verbeek, F.P., et al. (2014) Intraoperative Near-Infrared Fluorescence Imaging of Parathyroid Adenomas with Use of Low-Dose Methylene Blue. Head Neck, 36, 853-858. [Google Scholar] [CrossRef] [PubMed]
[11] Alander, J.T., Kaartinen, I., Laakso, A., et al. (2012) A Review of Indocyanine Green Fluorescent Imaging in Surgery. International Journal of Biomedical Imaging, 2012, Article ID: 940585. [Google Scholar] [CrossRef] [PubMed]
[12] Fanaropoulou, N.M., Chorti, A., Markakis, M., et al. (2019) The Use of Indocyanine Green in Endocrine Surgery of the Neck: A Systematic Review. Medicine (Baltimore), 98, e14765. [Google Scholar] [CrossRef
[13] De Gasperi, A., Mazza, E. and Prosperi, M. (2016) Indocyanine Green Kinetics to Assess Liver Function: Ready for a Clinical Dynamic Assessment in Major Liver Surgery? World Journal of Hepatology, 8, 355-367. [Google Scholar] [CrossRef] [PubMed]
[14] Bewick, J. and Pfleiderer, A. (2014) The Value and Role of Low Dose Methylene Blue in the Surgical Management of Hyperparathyroidism. The Annals of The Royal College of Surgeons of England, 96, 526-529. [Google Scholar] [CrossRef
[15] Perry, D., Bharara, M., Armstrong, D.G. and Mills, J. (2012) Intraoperative Fluorescence Vascular Angiography: During Tibial Bypass. Journal of Diabetes Science and Technology, 6, 204-208. [Google Scholar] [CrossRef] [PubMed]
[16] Martynov, V.I., Pakhomov, A.A., Popova, N.V., et al. (2016) Synthetic Fluorophores for Visualizing Biomolecules in Living Systems. Acta Naturae, 8, 33-46. [Google Scholar] [CrossRef
[17] Liu, J., Wang, X., Wang, R., et al. (2020) Near-Infrared Auto-Fluorescence Spectroscopy Combining with Fisher’s Linear Discriminant Analysis Improves Intraoperative Re-al-Time Identification of Normal Parathyroid in Thyroidectomy. BMC Surgery, 20, Article No. 4. [Google Scholar] [CrossRef] [PubMed]
[18] Tfelt-Hansen, J. and Brown, E.M. (2005) The Calcium-Sensing Receptor in Normal Physiology and Pathophysiology: A Review. Critical Reviews in Clinical Laboratory Sciences, 42, 35-70. [Google Scholar] [CrossRef] [PubMed]
[19] Squires, M.H., Jarvis, R., Shirley, L.A. and Phay, J.E. (2019) Intraoperative Parathyroid Autofluorescence Detection in Patients with Primary Hyperparathyroidism. Annals of Surgical Oncology, 26, 1142-1148. [Google Scholar] [CrossRef] [PubMed]