胃黄色瘤相关危险因素分析
Analysis of Risk Factors Associated with Gastric Xanthoma
DOI: 10.12677/ACM.2022.12121655, PDF,   
作者: 刘发蓉:青海大学研究生院,青海 西宁;费发珠, 白菊芳, 马颖才*:青海省人民医院消化内科,青海 西宁
关键词: 胃黄色瘤胃癌综述Gastric Xanthoma Gastric Cancer Review
摘要: 胃黄色瘤(gastric xanthoma, GX)是一种发生于胃黏膜的黄白色斑块,既往称为胃脂质小岛、网状内皮细胞瘤等。多见于有病理改变的胃黏膜,如慢性胃炎、肠化生或萎缩性胃炎等。近年来有研究表明该病可能与胃癌相关,并认为胃黄色瘤是一种癌前病变。本文中,作者将GX的病因、诊断及治疗进行了综述及梳理。
Abstract: Gastric xanthoma (GX) is a yellowish white plaque occurring in the gastric mucosa, which is pre-viously referred to as gastric lipid islet and reticuloendothelioma. It is more common in gastric mucosa with pathological changes, such as chronic gastritis, intestinal metaplasia or atrophic gas-tritis. In recent years, some studies have suggested that this disease may be related to gastric can-cer, and gastric xanthoma is considered as a precancerous lesion. In this paper, the etiology, diag-nosis and treatment of GX were reviewed.
文章引用:刘发蓉, 费发珠, 白菊芳, 马颖才. 胃黄色瘤相关危险因素分析[J]. 临床医学进展, 2022, 12(12): 11485-11490. https://doi.org/10.12677/ACM.2022.12121655

参考文献

[1] Sekikawa, A., Fukui, H., Sada, R., et al. (2016) Gastric Atrophy and Xanthelasma Are Markers for Predicting the De-velopment of Early Gastric Cancer. Journal of Gastroenterology, 51, 35-42. [Google Scholar] [CrossRef] [PubMed]
[2] 朱明山, 唐佳新, 梅进, 龚磊. 胃黄色瘤32例内镜下诊治分析[J]. 当代医学, 2010, 16(6): 55.
[3] Chen, Y., He, X.J., Zhou, M.J., et al. (2017) Gastric Xanthelasma and Meta-bolic Disorders: A Large Retrospective Study among Chinese Population. World Journal of Gastroenterology, 23, 7756-7764. [Google Scholar] [CrossRef] [PubMed]
[4] Sekikawa, A., Fukui, H., Maruo, T., et al. (2014) Gastric Xanthelasma May Be a Warning Sign for the Presence of Early Gastric Cancer. Journal of Gastroenterology & Hepatology, 29, 951-956. [Google Scholar] [CrossRef] [PubMed]
[5] Kitamura, S., Muguruma, N., Okamoto, K., et al. (2017) Clinicopathological Assessment of Gastric Xanthoma as Potential Predictive Marker of Gastric Cancer. Digestion, 96, 199-206. [Google Scholar] [CrossRef] [PubMed]
[6] Yamashita, K., Suzuki, R., Kubo, T., et al. (2019) Gastric Xanthomas and Fundic Gland Polyps as Endoscopic Risk Indicators of Gastric Cancer. Gut and Liver, 13, 409-414. [Google Scholar] [CrossRef] [PubMed]
[7] 陈莉, 王计, 彭华军, 吴小微. 胃黄色瘤的胃镜表现及临床病理特征[J]. 内科理论与实践, 2021, 16(2): 126-128.
[8] 王世杰, 毛涛, 田字彬. 胃黄色瘤的临床病理特征[J]. 青岛大学学报(医学版), 2018, 54(2): 229-232.
[9] Tang, S.J., Wu, R.N. and Bhaijee, F. (2014) Gastric Xanthelasma, Xanthoma, and Xanthomatosis. Video Journal and Encyclopedia of GI Endoscopy, 1, 625-627. [Google Scholar] [CrossRef
[10] Petrov, S., Churtchev, J., Mitova, R., et al. (1999) Xanthoma of the Stomach: Some Morphometrical Peculiarities and Scanning Electron Microscopy. Hepato Gastroenterology, 46, 1220-1222. [Google Scholar] [CrossRef] [PubMed]
[11] Gencosmanoglu, R., Sen-Oran, E., Kurtkaya-Yapicier, O., et al. (2004) Xanthelasmas of the Upper Gastrointestinal Tract. Journal of Gastroenterology, 39, 215-219. [Google Scholar] [CrossRef] [PubMed]
[12] Koksal, A., Suna, N., Kalkan, S.H., et al. (2016) Is Gastric Xanthelasma an Alarming Endoscopic Marker for Advanced Atrophic Gastritis and Intestinal Metaplasia? Digestive Diseases & Sciences, 61, 2949-2955.
[13] 崔俊华, 李懿皞, 周佳烨, 等. 幽门螺杆菌检测方法的发展与比较[J]. 检验医学, 2018, 33(1): 82-87.
[14] Sun, Y.Y. (2007) Dyslipidemia and H pylori in Gastric Xanthomatosis. World Journal of Gastroenterology, 13, 4598. [Google Scholar] [CrossRef] [PubMed]
[15] 熊秋棠, 王志峰, 何浪, 等. 胃黄色瘤与萎缩性胃炎相关性的单中心回顾性研究[J]. 胃肠病学, 2017, 22(9): 529-533.
[16] 苑坤, 于燕, 齐玲芝. 胃黄色瘤73例临床病理分析[J]. 吉林医学, 2012, 33(32): 7067-7068.
[17] 崔荣丽, 金珠. 胃黄色瘤临床病理分析312例[J]. 世界华人消化杂志, 2007, 15(6): 646-648.
[18] 骆元斌, 顾立萍, 黄小玲. 胃黄色瘤30例临床病理分析[J]. 西部中医药, 2013, 26(1): 119-120.
[19] 司明远. 胃黄色瘤的临床与病理[J]. 中国现代医药杂志, 2007, 9(8): 140.
[20] 梅宇宙. 胃黄色素瘤的内镜表现、病理特征及相关危险因素分析[D]: [硕士学位论文]. 宜昌: 三峡大学, 2021.
[21] Hunt, R., Xiao, S., Megraud, F., et al. (2011) Helicobacter pylori in Developing Countries. World Gastroenterology Organisation Global Guideline. Journal of Digestive Diseases, 12, 319-326. [Google Scholar] [CrossRef] [PubMed]
[22] Bruce, M.G. and Maaroos, H.I. (2008) Epidemiology of Helicobacter pylori Infection. Helicobacter, 13, 1-6. [Google Scholar] [CrossRef] [PubMed]
[23] Zhang, M., et al. (2014) Seroepidemiology of Helicobacter pylori Infection in Elderly People in the Beijing Region, China. World Journal of Gastroenterology, 20, 3635-3639. [Google Scholar] [CrossRef] [PubMed]
[24] Lin, P.Y., Brown, D.B. and Deppisch, L.M. (1989) Gastric Xanthelasma in Hyperplastic Gastric Polyposis. Archives of Pathology & Laboratory Medicine, 113, 428-430.
[25] Carmack, S.W., Genta, R.M., Schuler, C.M., et al. (2009) The Current Spectrum of Gastric Polyps: A 1-Year National Study of over 120,000 Patients. American Journal of Gastroenterology, 104, 1524-1532. [Google Scholar] [CrossRef] [PubMed]
[26] Fukuda, S.I., Akahoshi, K., Fushimi, F., et al. (2015) Gastric Hyper-plastic Polyp with Xanthoma Observed by Magnification Narrow-Band Imaging Endoscopy and Endoscopic Ultraso-nography: Report of a Case. Fukuoka igaku zasshi = Hukuoka Acta Medica, 106, 77.
[27] 吴忆雪. 胃黄色瘤临床流行病学特点及与慢性萎缩性胃炎相关性研究[D]: [硕士学位论文]. 北京: 北京中医药大学, 2020.
[28] Hori, S. and Tsutsumi, Y. (2010) Helicobacter pylori Infection in Gastric Xanthomas: Immunohistochemical Analysis of 145 Lesions. Pathology International, 46, 589-593. [Google Scholar] [CrossRef] [PubMed]
[29] Isomoto, H., Mizuta, Y., Inoue, K., et al. (1999) A Close Relationship between Helicobacter pylori Infection and Gastric Xanthoma. Scandinavian Journal of Gastroenterology, 34, 346-352. [Google Scholar] [CrossRef] [PubMed]
[30] 徐玉松. 胃黄色瘤与幽门螺杆菌感染的相关性分析[J]. 中国继续医学教育, 2017, 9(36): 16-18.
[31] Nostrant, T.T., Dobbins, W.O., Agha, F.P., et al. (1986) Gastric Xanthomatosis and Cholestasis. Digestive Diseases & Sciences, 31, 925-928. [Google Scholar] [CrossRef
[32] 张淑芳, 姚萍. 胃黄色瘤相关危险因素的研究进展[J]. 世界最新医学信息文摘, 2019, 19(37): 121-122.
[33] Shibukawa, N., Ouchi, S., Wakamatsu, S., et al. (2017) Gastric Xanthoma Is a Predictive Marker for Metachronous and Synchronous Gastric Cancer. World Journal of Gastrointestinal Oncology, 9, 327-332. [Google Scholar] [CrossRef] [PubMed]
[34] Shibukawa, N., Ouchi, S., Wakamatsu, S., et al. (2020) Gastric Xanthoma Is Correlated with Early Gastric Cancer of Previously Helicobacter pylori-Infected Gastric Mucosa. JGH Open, 5, 249-252.
[35] Shibukawa, N., et al. (2018) Gastric Xanthoma Is a Predictive Marker for Early Gastric Cancer Detected after Helicobacter pylori Eradication. Internal Medicine (Tokyo, Japan), 58, 779-784. [Google Scholar] [CrossRef] [PubMed]
[36] 王玉红, 张若梅, 刘先勇. 健脾活血方治疗胃黄色瘤临床研究[J]. 河北中医, 2021, 43(6): 951-954.