mNGS在肺部感染应用中的研究进展
Research Progress of mNGS in Pulmonary Infection
DOI: 10.12677/ACM.2023.131066, PDF,   
作者: 裴红运：济宁医学院临床医学院，山东 济宁；山凤莲*：济宁医学院附属医院呼吸与危重症医学科，山东 济宁
关键词: 肺部感染；宏基因组二代测序；病原体检测；Lung Infection； Metagenome Second-Generation Sequencing； Pathogen Detection
摘要: 肺部感染是目前临床常见的呼吸系统感染性疾病之一，易合并各种并发症，致死率高，严重威胁人类健康。其致病病原体涵盖范围广，且易合并感染。而目前传统病原体检测方式具有耗时长、阳性率低等情况，会影响肺部感染的早期诊断。宏基因组二代测序技术(mNGS)是近几年发展起来的一种高通量测序技术，与传统方法相比能快速、准确检测出病原体。
Abstract: Pulmonary infection is one of the common respiratory infectious diseases, which is easy to be com-plicated with various complications and has a high mortality rate, and seriously threatens human health. Its pathogenic pathogens cover a wide range, and are easy to co-infect. However, the tradi-tional pathogen detection methods have the disadvantages of long time consuming and low positive rate, which will affect the early diagnosis of pulmonary infection. Metagenome second-generation sequencing (mNGS) is a high-throughput sequencing technology developed in recent years, which can detect pathogens quickly and accurately compared with traditional methods.
文章引用：裴红运, 山凤莲. mNGS在肺部感染应用中的研究进展[J]. 临床医学进展, 2023, 13(1): 436-441. https://doi.org/10.12677/ACM.2023.131066

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