金莲花临床应用研究进展

Application of Biotechnology in Medicinal Plants

摘要: 金莲花是在临床应用广泛的中药材。其味苦、性寒，市面上常用的剂型是软胶囊、片和颗粒剂，临床上可用于乳腺癌等肿瘤疾病、上呼吸道感染、咽炎、扁桃体炎、牙周炎等炎症或急性病症及手足口病等多种疾病的治疗。目前，国内关于金莲花相关研究较为完善，根据近年来的文献整合明显观察到其疗效确切、不良反应少，故常用于儿童。本文主要通过将近几年金莲花在抗肿瘤、抗炎、抗氧化等重要临床应用方面进行梳理与归纳，争取为促进该药材的临床合理应用和新药研发提供理论参考。

Abstract: Biotechnology is a common research technology in the development of modern science and has been widely used in various fields. As a country rich in medicinal plant resources, China has paid more and more attention to the identification, classification, protection and development of medicinal plants. DNA barcoding is a rapid and accurate method for species identification using relatively short standard DNA fragments, which can make up for the shortcomings of traditional identification methods. Molecular Marker Technique has been widely used in the study of medicinal plants because of its advantages of simple operation, high sensitivity and accurate results. In this paper, the characteristics, types and applications of DNA barcoding and molecular markers in medicinal plants are reviewed, which can provide references for plant identification, genetic breeding, germplasm protection and development and utilization, and is of great significance for further study on genetic relationship analysis and genetic diversity.