FGF23、Klotho在慢性阻塞性肺疾病中的研究进展
The Research Progress of FGF23 and Klotho in Chronic Obstructive Pulmonary Disease
DOI: 10.12677/ACM.2023.131112, PDF,   
作者: 张妮妮:延安大学医学院,陕西 延安;李 莉*, 何 达, 张 莉:榆林市第一医院呼吸与危重症医学科,陕西 榆林
关键词: 慢性阻塞性肺疾病成纤维细胞生长因子23KlothoChronic Obstructive Pulmonary Disease Fibroblast Growth Factor 23 Klotho
摘要: 慢性阻塞性肺疾病(Chronic Obstructive Pulmonary Disease, COPD)是全球高发病率和死亡率的重要原因,造成了巨大的经济和社会负担。近年来研究发现,成纤维细胞生长因子23 (Fibroblast Growth Factor 23, FGF23)、Klotho除了参与体内的钙磷代谢调节外,同时与COPD发病机制密切相关。FGF23、Klotho的深入研究有望为临床治疗COPD带来新的突破。
Abstract: Chronic obstructive pulmonary disease (COPD) is an important cause of high morbidity and mortal-ity in the world which results in a huge economic and social burden. In recent years, it has been found that fibroblast growth factor 23 (FGF23) and Klotho are not only involved in the regulation of calcium and phosphorus metabolism in vivo, but also related to the pathogenesis of COPD. The fur-ther study of FGF23 and Klotho may bring a new breakthrough in the clinical treatment of COPD.
文章引用:张妮妮, 李莉, 何达, 张莉. FGF23、Klotho在慢性阻塞性肺疾病中的研究进展[J]. 临床医学进展, 2023, 13(1): 772-778. https://doi.org/10.12677/ACM.2023.131112

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