恶性肿瘤合并转移的治疗进展
Advances in the Treatment of Malignant Tumors with Metastasis
DOI: 10.12677/ACM.2023.131153, PDF,   
作者: 柳 刚, 秦 伟:青海大学,青海 西宁
关键词: 恶性肿瘤寡转移调控影响Malignant Tumor Oligo Transfer Regulation Influence
摘要: 食管胃结合部癌是一种可怕的恶性肿瘤,全球发病率正在上升,总体预后仍然很差。在其诊断时,相当一部分的食管胃结合部癌患者有远处转移,被认为是无法治愈的。许多学者不建议对转移性疾病进行手术治疗。尽管有这些建议,有限转移性(寡转移性)食管胃结合部癌的治疗目前正在向更积极且多模式的方向转变,其中囊括了分子生物学及新的治疗手段的应用,且在临床工作中确实观察到了受益。笔者在阅读大量文献及相关资料的前提下,总结了食管胃结合部癌特有的分子水平的转移机制,梳理了新的诊疗方法,并以此为基础探讨了可行性和其前景。
Abstract: Esophagogastric junction cancer is a terrible malignant tumor, the global incidence rate is rising, and the overall prognosis is still poor. At the time of diagnosis, a considerable number of patients with cancer at the junction of esophagus and stomach had distant metastasis, which was considered to be incurable. Many scholars do not recommend surgical treatment for metastatic diseases. De-spite these suggestions, the treatment of limited metastatic (oligometastatic) esophagogastric junc-tion cancer is currently changing to a more active and multi-mode direction, which includes the ap-plication of molecular biology and new treatment methods, and has indeed seen benefits in clinical work. On the premise of reading a large number of literature and relevant materials, the author summarized the specific molecular level metastasis mechanism of esophageal gastric junction can-cer, combed out new diagnosis and treatment methods, and discussed the feasibility and prospects on this basis.
文章引用:柳刚, 秦伟. 恶性肿瘤合并转移的治疗进展[J]. 临床医学进展, 2023, 13(1): 1109-1117. https://doi.org/10.12677/ACM.2023.131153

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