血栓形成后综合征的治疗及预防
Prevention and Treatment of the Post-Thrombotic Syndrome
DOI: 10.12677/ACM.2023.132226, PDF,   
作者: 张 涛：重庆医科大学附属第二医院，重庆
关键词: 血栓形成后综合征；预防；治疗；Post-Thrombotic Syndrome； Prevention； Treatment
摘要: 下肢深静脉血栓形成后综合征(PTS)是继发于下肢深静脉血栓形成(DVT)的一组疾病。目前PTS的发生机制尚不明确，但其较高的发病率及危害性已严重影响患者的生活质量。本文将对血栓形成后治疗及预防等研究进展进行综述。
Abstract: Post-thrombotic syndrome (PTS) is a group of diseases secondary to deep vein thrombosis (DVT) of the lower extremities. At present, the pathogenesis of PTS is not clear, but its high incidence rate and harmfulness have seriously affected the quality of life of patients. This article will review the research progress of post-thrombosis treatment and prevention.
文章引用：张涛. 血栓形成后综合征的治疗及预防[J]. 临床医学进展, 2023, 13(2): 1636-1644. https://doi.org/10.12677/ACM.2023.132226

参考文献

[1] Kahn, S.R., Shapiro, S., Wells, P.S., et al. (2014) Compression Stockings to Prevent Post-Thrombotic Syndrome: A Randomised Placebo-Controlled Trial. The Lancet, 383, 880-888. [Google Scholar] [CrossRef] 
[2] Engeseth, M., Enden, T., Sandset, P.M., et al. (2019) Limita-tions of the Villalta Scale in Diagnosing Post-Thrombotic Syndrome. Thrombosis Research, 184, 62-66. [Google Scholar] [CrossRef] [PubMed]
[3] Ning, J.J., Ma, W.D., Fish, J., et al. (2020) Biases of Villalta Scale in Classifying Post-Thrombotic Syndrome in Patients with Pre-Existing Chronic Venous Disease. Journal of Vas-cular Surgery: Venous and Lymphatic Disorders, 8, 1025-1030. [Google Scholar] [CrossRef] [PubMed]
[4] Wik, H.S., Enden, T.R., Ghanima, W., et al. (2018) Diagnostic Scales for the Post-Thrombotic Syndrome. Thrombosis Research, 164, 110-115. [Google Scholar] [CrossRef] [PubMed]
[5] Cruddas, L., Onida, S. and Davies, A.H. (2021) What, If An-ything, Should Replace the Villalta Score for Post Thrombotic Syndrome? Phlebology, 36, 595-596. [Google Scholar] [CrossRef] [PubMed]
[6] Rabinovich, A., Ducruet, T., Kahn, S.R., et al. (2018) Develop-ment of a Clinical Prediction Model for the Postthrombotic Syndrome in a Prospective Cohort of Patients with Proximal Deep Vein Thrombosis. Journal of Thrombosis and Haemostasis, 16, 262-270. [Google Scholar] [CrossRef] [PubMed]
[7] Amin, E.E., van Kuijk, S.M.J., Joore, M.A., et al. (2018) Development and Validation of a Practical Two-Step Prediction Model and Clinical Risk Score for Post-Thrombotic Syndrome. Throm-bosis and Haemostasis, 118, 1242-1249. [Google Scholar] [CrossRef] [PubMed]
[8] Kahn, S.R. (2016) The Post-Thrombotic Syndrome. Hematology, ASH Education Program, 2016, 413-418. [Google Scholar] [CrossRef] [PubMed]
[9] Prandoni, P., Lensing, A.W.A., Prins, M.H., et al. (2019) Determinants of Severe Post-Thrombotic Syndrome: The Role of Thrombus Location. Thrombosis Research, 178, 171-172. [Google Scholar] [CrossRef] [PubMed]
[10] Cucuruz, B., Kopp, R., Pfister, K., et al. (2020) Risk and Protective Factors for Post-Thrombotic Syndrome after Deep Venous Thrombosis. Journal of Vascular Surgery: Venous and Lymphatic Disorders, 8, 390-395. [Google Scholar] [CrossRef] [PubMed]
[11] Nishimoto, Y., Yamashita, Y., Morimoto, T., et al. (2019) Risk Factors for Post-Thrombotic Syndrome in Patients with Deep Vein Thrombosis: From the COMMAND VTE Registry. Heart Vessels, 34, 669-677. [Google Scholar] [CrossRef] [PubMed]
[12] Kahn, S.R., Comerota, A.J., Cushman, M., et al. (2014) The Postthrombotic Syndrome: Evidence-Based Prevention, Diagnosis, and Treatment Strategies: A Scientific Statement from the American Heart Association. Circulation, 130, 1636-1661. [Google Scholar] [CrossRef] 
[13] Rabinovich, A. and Kahn, S.R. (2018) How I Treat the Postthrombotic Syndrome. Blood, 131, 2215-2222. [Google Scholar] [CrossRef] [PubMed]
[14] Visona, A., Quere, I., Mazzolai, L., et al. (2021) Post-Thrombotic Syndrome. Vasa, 50, 331-340. [Google Scholar] [CrossRef] [PubMed]
[15] Cosmi, B., Stanek, A., Kozak, M., et al. (2022) The Post-Thrombotic Syndrome-Prevention and Treatment: VAS-Euro- pean Independent Foundation in Angiology/Vascular Medicine Position Paper. Frontiers in Cardiovascular Medicine, 9, Article ID: 762443. [Google Scholar] [CrossRef] [PubMed]
[16] Partsch, H. and Blättler, W. (2000) Compression and Walking versus Bed Rest in the Treatment of Proximal Deep Venous Thrombosis with Low Molecular Weight Heparin. Journal of Vascular Surgery, 32, 861-869. [Google Scholar] [CrossRef] [PubMed]
[17] Amin, E.E., Joore, M.A., Ten Cate, H., et al. (2018) Clinical and Economic Impact of Compression in the Acute Phase of Deep Vein Thrombosis. Journal of Thrombosis and Haemosta-sis, 16, 1555-1563. [Google Scholar] [CrossRef] [PubMed]
[18] Amin, E.E., Bistervels, I.M., Meijer, K., et al. (2018) Reduced Incidence of Vein Occlusion and Postthrombotic Syndrome after Immediate Compression for Deep Vein Thrombosis. Blood, 132, 2298-2304. [Google Scholar] [CrossRef] [PubMed]
[19] Kahn, S.R., Shrier, I., Shapiro, S., et al. (2011) Six-Month Exercise Training Program to Treat Post-Thrombotic Syndrome: A Randomized Controlled Two-Centre Trial. CMAJ, 183, 37-44. [Google Scholar] [CrossRef] [PubMed]
[20] Vedantham, S. (2017) Knowns and Unknowns in Managing Postthrombotic Syndrome. Seminars in Interventional Radiology, 34, 68-72. [Google Scholar] [CrossRef] [PubMed]
[21] Galanaud, J.-P., Monreal, M. and Kahn, S.R. (2018) Epidemiology of the Post-Thrombotic Syndrome. Thrombosis Research, 164, 100-109. [Google Scholar] [CrossRef] [PubMed]
[22] Lattimer, C.R., Kalodiki, E., Azzam, M., et al. (2014) Valida-tion of the Villalta Scale in Assessing Post-Thrombotic Syndrome Using Clinical, Duplex, and Hemodynamic Compara-tors. Journal of Vascular Surgery: Venous and Lymphatic Disorders, 2, 8-14. [Google Scholar] [CrossRef] [PubMed]
[23] Maleti, O. and Perrin, M. (2011) Reconstructive Surgery for Deep Vein Reflux in the Lower Limbs: Techniques, Results and Indications. European Journal of Vascular and Endovascular Surgery, 41, 837-848. [Google Scholar] [CrossRef] [PubMed]
[24] Palma, E.C. and Esperon, R. (1960) Vein Transplants and Grafts in the Surgical Treatment of the Postphlebitic Syndrome. The Journal of Cardiovascular Surgery (Torino), 1, 94-107.
[25] Husni, E.A. (1983) Reconstruction of Veins: The Need for Objectivity. The Journal of Cardiovascular Surgery (Torino), 24, 525-528.
[26] Comerota, A.J., Grewal, N.K., Thakur, S., et al. (2010) Endovenectomy of the Common Femoral Vein and Intraoperative Iliac Vein Recanalization for Chronic Iliofemoral Venous Occlusion. Journal of Vascular Surgery, 52, 243-247. [Google Scholar] [CrossRef] [PubMed]
[27] Vogel, D., Comerota, A.J., Al-Jabouri, M., et al. (2012) Common Femoral Endovenectomy with Iliocaval Endoluminal Recanalization Improves Symptoms and Quality of Life in Patients with Postthrombotic Iliofemoral Obstruction. Journal of Vascular Surgery, 55, 129-135. [Google Scholar] [CrossRef] [PubMed]
[28] Jalaie, H., Schleimer, K., Barbati, M.E., et al. (2016) Interventional Treatment of Postthrombotic Syndrome. Gefasschirurgie, 21, 37-44. [Google Scholar] [CrossRef] [PubMed]
[29] van Vuuren, T.M.A.J., de Wolf, M.A.F., Arnoldussen, C.W.K.P., et al. (2017) Editor’s Choice—Reconstruction of the Femoro-Ilio-Caval Outflow by Percutaneous and Hybrid Interven-tions in Symptomatic Deep Venous Obstruction. European Journal of Vascular and Endovascular Surgery, 54, 495-503. [Google Scholar] [CrossRef] [PubMed]
[30] Berger, A., Jaffe, J.W. and York, T.N. (1995) Iliac Compression Syndrome Treated with Stent Placement. Journal of Vascular Surgery, 21, 510-514. [Google Scholar] [CrossRef] 
[31] Qiu, P., Zha, B.S., Xu, A., et al. (2019) Systematic Review and Meta-Analysis of Iliofemoral Stenting for Post- Thrombotic Syndrome. European Journal of Vascular and Endo-vascular Surgery, 57, 407-416. [Google Scholar] [CrossRef] [PubMed]
[32] Schleimer, K., Barbati, M.E., Grommes, J., et al. (2019) Update on Diagnosis and Treatment Strategies in Patients with Post-Thrombotic Syndrome Due to Chronic Venous Obstruction and Role of Endovenous Recanalization. Journal of Vascular Surgery: Venous and Lymphatic Disorders, 7, 592-600. [Google Scholar] [CrossRef] [PubMed]
[33] Seager, M.J., Busuttil, A., Dharmarajah, B., et al. (2016) Editor’s Choice—A Systematic Review of Endovenous Stenting in Chronic Venous Disease Secondary to Iliac Vein Obstruction. European Journal of Vascular and Endovascular Surgery, 51, 100-120. [Google Scholar] [CrossRef] [PubMed]
[34] Prandoni, P., Noventa, F., Quintavalla, R., et al. (2012) Thigh-Length versus Below-Knee Compression Elastic Stockings for Prevention of the Postthrombotic Syndrome in Pa-tients with Proximal-Venous Thrombosis: A Randomized Trial. Blood, 119, 1561-1565. [Google Scholar] [CrossRef] [PubMed]
[35] Ten, C.-H.A.J., Amin, E.E., Bouman, A.C., et al. (2018) Indi-vidualised versus Standard Duration of Elastic Compression Therapy for Prevention of Post-Thrombotic Syndrome (IDEAL DVT): A Multicentre, Randomised, Single-Blind, Allocation-Concealed, Non-Inferiority Trial. The Lancet Haematology, 5, e25-e33.
[36] Haig, Y., Enden, T., Grøtta, O., et al. (2016) Post-Thrombotic Syndrome after Cathe-ter-Directed Thrombolysis for Deep Vein Thrombosis (CaVenT): 5-Year Follow-Up Results of an Open-Label, Ran-domised Controlled Trial. The Lancet Haematology, 3, e64-e71. [Google Scholar] [CrossRef] 
[37] Vedantham, S., Goldhaber, S.Z., Julian, J.A., et al. (2017) Pharmacomechanical Catheter-Directed Thrombolysis for Deep-Vein Thrombosis. The New England Journal of Medicine, 377, 2240-2252. [Google Scholar] [CrossRef] 
[38] Notten, P., Ten Cate-Hoek, A.J., Arnoldussen Carsten, W.K.P., et al. (2020) Ultrasound-Accelerated Catheter-Directed Thrombolysis versus Anticoagulation for the Prevention of Post-Thrombotic Syndrome (CAVA): A Single-Blind, Multicentre, Randomised Trial. The Lancet Haematology, 7, e40-e49. [Google Scholar] [CrossRef] 
[39] Prandoni, P., Ageno, W., Ciammaichella, M., et al. (2020) The Risk of Post-Thrombotic Syndrome in Patients with Proximal Deep Vein Thrombosis Treated with the Direct Oral Anticoagulants. Internal and Emergency Medicine, 15, 447-452. [Google Scholar] [CrossRef] [PubMed]
[40] Li, R.H., Yuan, M.Q., Cheng, J.N., et al. (2020) Risk of Post-Thrombotic Syndrome after Deep Vein Thrombosis Treated with Rivaroxaban versus Vitamin-K Antagonists: A Systematic Review and Meta-Analysis. Thrombosis Research, 196, 340-348. [Google Scholar] [CrossRef] [PubMed]
[41] Ferreira, T., Huber, S.C., de Moraes, M.B., et al. (2020) Low Prevalence of Post-Thrombotic Syndrome in Patients Treated with Rivaroxaban. Vascular Pharmacology, 124, Article ID: 106608. [Google Scholar] [CrossRef] [PubMed]
[42] Robertson, L., McBride, O. and Burdess, A. (2016) Pharmacome-chanical Thrombectomy for Iliofemoral Deep Vein Thrombosis. The Cochrane Database of Systematic Reviews, 11, CD011536. [Google Scholar] [CrossRef] 
[43] 李晓强, 张福先, 王深明. 深静脉血栓形成的诊断和治疗指南(第三版) [J]. 中国血管外科杂志(电子版), 2017, 9(4): 250-257.

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