宫腔粘连病因及诊治研究进展

Advances in the Etiology and Therapy of In-trauterine Adhesions

摘要: 宫腔粘连是各种病因素作用下的子宫内膜自行修复功能损伤性疾病，严重影响女性生育功能。妊娠期宫腔操作是导致宫腔粘连的主要病因，宫腔感染、子宫内膜修复障碍等也可能与该病的发生密切相关。宫腔镜检查是诊断宫腔粘连的金标准，宫腔镜宫腔粘连分离术是治疗IUA的首选方法，术后多需联用辅助治疗措施预防再粘连发生，但目前尚未对该病的最佳诊疗方案达成统一的评价标准。早发现、早诊断并及时采取措施提供依据，预防IUA，避免对子宫内膜造成更严重的伤害，为宫腔粘连的治疗开辟新思路。

Abstract: Intrauterine adhesion (IUA) is an endometrial injury disease caused by various pathogenic factors, which seriously affects female genital health and reproductive function. Intrauterine operation during pregnancy is the main cause of IUA. Furthermore, intrauterine infection and less perfusion of endometrial blood flow may also be closely related to the onset and progress of the disease. Hys-teroscopy is the gold standard for clinical diagnosis and treatment of IUA. Transcervical resection of adhesion is currently an effective method to deal with IUA. Postoperative adjuvant treatment is used to prevent adhesion recurrence, but there is no consensus on the best diagnosis and treatment plan for this disease. This article reviews the clinical etiology, diagnosis and therapy of IUA, aiming at providing further evidence for its early detection and prevention, precise diagnosis and timely treatment, so as to avoid severe damage to the uterine endometrium, and provides a reference for clinical decision-making.